Which is treatment of choice in eclampsia?
The drug of choice to treat and prevent eclampsia is magnesium sulfate. Familiarity with second-line medications phenytoin and diazepam/lorazepam is required for cases in which magnesium sulfate may be contraindicated (eg, myasthenia gravis) or ineffective.
What is Pritchard regimen?
The Pritchard regimen is a predominantly intramuscular (IM) regimen given as a loading dose of 4 g intravenously (IV) and 5 g IM into each buttock followed by a maintenance dose of 5 g IM every 4 h 19.
What is the definitive treatment of pre eclampsia eclampsia and why?
Treatment for pre-eclampsia focuses on lowering blood pressure and managing the other symptoms, sometimes with medication. The only way to cure pre-eclampsia is to deliver the baby. In some cases this may mean inducing labour (starting labour artificially), although this depends on how far along the pregnancy is.
What is the difference between eclampsia and pre eclampsia?
Preeclampsia and eclampsia are pregnancy-related high blood pressure disorders. Preeclampsia is a sudden spike in blood pressure. Eclampsia is more severe and can include seizures or coma.
How is severe eclampsia treated?
Possible treatment for preeclampsia may include:
- Medications to lower blood pressure. These medications, called antihypertensives, are used to lower your blood pressure if it’s dangerously high.
- Corticosteroids.
- Anticonvulsant medications.
What do you give for eclampsia?
In severe cases of preeclampsia, doctors often recommend antiseizure medications, such as magnesium sulfate. Magnesium sulfate is a mineral that reduces seizure risks in women with preeclampsia. A healthcare provider will give the medication intravenously.
How do you give diazepam in eclampsia?
A loading dose of 4-6 g (15-20 min) and a maintenance dose of 1-2 g per hour as a continuous IV solution should be administered. Alternatively, lorazepam (Ativan; 4 mg IV over 2-5 minutes) or diazepam (Valium; 5-10 mg IV slowly) can be used to terminate the seizure, after which magnesium sulfate is administered.
What is lytic cocktail for?
Lytic cocktail is a mixture of drugs used for women with eclampsia; these are usually chlorpromazine, promethazine and pethidine (meperidine). First introduced in India (Menon 1961), this combination of drugs was thought to lower blood pressure and sedate the central nervous system.
What is zuspan regimen?
In the Zuspan regimen, the loading dose consists of an initial intravenous dose of 4 g slowly over 5-10 min followed by a maintenance dose of 1-2 g every hour given by an infusion pump. A gravity fed infusion set can be used in the absence of the pump especially in the developing countries.
