What is triangulation virus?
The triangulation number is defined as the square of the distance between 2 adjacents 5-fold vertices.
What is a icosahedral virus?
Most viruses have icosahedral or helical capsid structure, although a few have complex virion architecture. An icosahedron is a geometric shape with 20 sides, each composed of an equilateral triangle, and icosahedral viruses increase the number of structural units in each face to expand capsid size.
What are pentamers and hexamers?
Pentamers of subunits are colored red, and hexamers of subunits are colored in shades of yellow and orange. Its capsid is just big enough to hold a single strand of RNA that encodes only one protein: the capsid subunit.
How many hexamers are in t3?
If one only focuses on the 12 pentamers (more precisely, 11 pentamers and a putative portal) and 80 hexamers, then its structure would be classified as T(3,0)=919.
What is an example of an icosahedral virus?
Viruses with icosahedral structures are released into the environment when the cell dies, breaks down and lyses, thus releasing the virions. Examples of viruses with an icosahedral structure are the poliovirus, rhinovirus, and adenovirus.
What do capsids do?
The capsid has three functions: 1) it protects the nucleic acid from digestion by enzymes, 2) contains special sites on its surface that allow the virion to attach to a host cell, and 3) provides proteins that enable the virion to penetrate the host cell membrane and, in some cases, to inject the infectious nucleic …
What is symmetry virus?
Self assembly of virus capsids follows two basic patterns: helical symmetry, in which the protein subunits and the nucleic acid are arranged in a helix, and icosahedral symmetry, in which the protein subunits assemble into a symmetric shell that covers the nucleic acid-containing core.
Is Ebola an enveloped virus?
The Ebola virus is an “enveloped virus,” meaning that the core of the virus is surrounded by a lipoprotein outer layer. Enveloped viruses such as Ebola are more susceptible to destruction with a number of physical and chemical agents than viruses without lipoprotein envelopes (Figure).
Which is the best description of a hexamer?
As is well known, the prediction of protein quaternary structure attributes (such as monomer, dimmer, trimer, tetramer, pentamer, hexamer, heptamer, and octamer) plays an important role in the structure bioinformatics.
How are random hexamers used in reverse transcription?
Random hexamers are a mixture of all possible combinations of six nucleotide sequences that can attach randomly to mRNA and initiate reverse transcription of the entire RNA pool. From: Diagnostic Immunohistochemistry (Third Edition), 2011.
Are there any human viruses with this structure?
So far no human viruses with this structure are known There are also the ‘unconventional agents’ sometimes known as ‘unconventional viruses’ or ‘atypical viruses’ – Up to now, the main kinds that have been studied are viroids and prions.
How are the capsomers of a virus arranged?
Capsomers at the 12 corners have a 5-fold symmetry and interact with 5 neighboring capsomers, and are thus known as pentons or pentamers (figure 3E). Larger viruses contain more capsomers; extra capsomers are arranged in a regular array on the faces of the icosahedrons.
