What is the zeta potential of gold nanoparticles?
The LSPR of gold nanoparticles36 has been exploited to assess the degree of nanoparticle stability as a function of surface chemistry and local environment. Zeta potential measurements reveal the nanoparticles are highly stable and have an average surface charge of −39.7 ± 0.7 mV at pH 9.3.
Why do gold nanoparticles from 1 to 10 nm produce different colors?
The surface charge of the gold nanoparticle becomes neutral, causing nanoparticles to aggregate. As a result, the solution color changes from red to blue.
What is high zeta potential?
The magnitude of the zeta potential indicates the degree of electrostatic repulsion between adjacent, similarly charged particles in a dispersion. For molecules and particles that are small enough, a high zeta potential will confer stability, i.e., the solution or dispersion will resist aggregation.
What are the properties of gold nanoparticles?
Properties of gold nanoparticles Spherical AuNPs possess useful attributes such as size- and shape-related optoelectronic properties,18 large surface-to-volume ratio, excellent biocompatibility, and low toxicity. These properties make AuNPs an important tool in bionanotechnology (Table 1).
What are the potential applications of gold nanoparticles?
Gold nanoparticles have a broad spectrum of application areas including medicine, food industry, water purification, and biological applications [112]. In particular, gold nanoparticles are applied to drug-delivery, photo-thermal therapy, imaging, sensing, catalysis, and even antimicrobials [112,113].
What are the nano tools used for targeted drug delivery?
Nanoparticles used in drug delivery system
- Chitosan. Chitosan exhibits muco-adhesive properties and can be used to act in the tight epithelial junctions.
- Alginate.
- Xanthan gum.
- Cellulose.
- Liposomes.
- Polymeric micelles.
- Dendrimers.
- Inorganic nanoparticles.
What are the benefits of gold nanoparticles?
Gold nanoparticles have been explored as drug carriers due to the following advantages: (1) the large surface area provides high loading capacity for drug loading and improves the hydrophilicity and stability of drugs; (2) the ability to modify surface with targeting ligands to enhance the tumor selective accumulation …
Why are gold nanoparticles toxic?
Due to the negative surface charge, gold nanoparticles can be adsorbed by serum proteins and thus contribute to cellular uptake. 2-nm citrate-stabilized gold particles were toxic to PC-3 and MCF-7 cells in a time- and dose dependent manner when tested by both MTT and LDH.
