What is the treatment for hyperphosphatemia?
In addition to diet and dialysis, you’ll probably need medication to help your body remove excess phosphate. A few drugs help reduce the amount of phosphate your intestines absorb from foods you eat. These include: calcium-based phosphate binders (calcium acetate and calcium carbonate)
Which medication is most commonly used to treat hyperphosphatemia?
Aluminum Hydroxide: The antacid aluminum hydroxide (various formulations) is a phosphate binder used to treat hyperphosphatemia.
What is a phosphate binder medication?
Phosphate binders are used to decrease the absorption of phosphate from food in the digestive tract. They are used when there is an abnormally high blood phosphate level (hyperphosphatemia) which can be caused by impaired renal phosphate excretion or increased extracellular fluid phosphate loads.
What leads to hyperphosphatemia?
Hyperphosphatemia is a serum phosphate concentration > 4.5 mg/dL (> 1.46 mmol/L). Causes include chronic kidney disease, hypoparathyroidism, and metabolic or respiratory acidosis. Clinical features may be due to accompanying hypocalcemia and include tetany. Diagnosis is by serum phosphate measurement.
How is hyperphosphatemia treated in hypoparathyroidism?
Given with meals, the oral calcium can ameliorate the hyperphosphatemia of hypoparathyroidism, although this effect has to be carefully balanced against the phosphate absorption–promoting effects of the vitamin D. Over the long term, this therapy may result in nephrocalcinosis.
What causes hyperphosphatemia?
What OTC reduces hyperphosphatemia?
Drugs used to treat Hyperphosphatemia
Drug name | Rating | Rx/OTC |
---|---|---|
View information about PhosLo PhosLo | 8.0 | Rx/OTC |
Generic name: calcium acetate systemic Drug class: minerals and electrolytes, phosphate binders For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
Does calcium bind with phosphorus?
The phosphate builds up in your body and binds to calcium. This causes your calcium levels to decrease, which may weaken your bones. The phosphate and calcium can narrow your blood vessels and increase your risk of heart disease and stroke.
What is a natural phosphorus binder?
You can keep you phosphorus level normal by understanding your diet and medications for phosphorus control. Phosphorus can be found in foods (organic phosphorus) and is naturally found in protein-rich foods such as meats, poultry, fish, nuts, beans and dairy products.
Does calcium carbonate reduce phosphate?
Calcium carbonate produced positive calcium balance, did not affect phosphorus balance, and produced only a modest reduction in urine phosphorus excretion compared with placebo.
Is magnesium a phosphate binder?
Magnesium compounds have been tried as phosphate binders since the early aluminum binder era. Early studies using magnesium hydroxide were complicated by diarrhea or mild hyperkalemia. 11, 12 Magnesium carbonate was used more successfully in both hemodialysis and peritoneal dialysis patients.
When to treat hypophosphatemia?
Refeeding hypophosphatemia can be anticipated in patients who have a strong history of alcoholism, starvation, or anorexia/bulimia. Adequate treatment includes phosphate supplements in addition to feeding and attention to underlying eating disorders or substance abuse.
What medications increase phosphorus levels?
Many common over-the-counter and prescription drugs can elevate alkaline phosphatase levels. For example, hypertension drugs such as propanolol or verapamil or gout treatments such as allopurinol can raise levels. Antibiotics such as erythomycin and ulcer treatments such as ranitidine are also common culprits.
What medications are high in phosphorus?
Drugs that may increase phosphorus levels include anabolic steroids, β-adrenergic blockers, ergocalciferol, furosemide, hydrochlorothiazide, methicillin (occurs with nephrotoxicity), oral contraceptives, parathyroid extract, phosphates, sodium etidronate , tetracycline (occurs with nephrotoxicity), and vitamin D.
What is the treatment for high phosphorus levels?
High phosphorous levels require additional zinc and iron treatments for plants to maintain their health. Texas A&M University suggests mixing a spray that contains water with 1 percent foliar zinc and iron, then applying that spray to plants every week if phosphorous levels are excessively high.