What is Omas syndrome?

Opsoclonus-myoclonus-ataxia syndrome (often referred to as OMAS or opsoclonus-myoclonus syndrome) is an autoimmune disorder of the nervous system characterized by new movements of the limbs and eyes, abnormal behaviors, sleep dysregulation, and difficulty talking.

What is opsoclonus-myoclonus syndrome?

Opsoclonus-myoclonus syndrome (OMS) is an inflammatory neurological disorder, often with paraneoplastic etiology. It is characterized by associated ocular, motor, behavioral, sleep, and language disturbances. The onset is usually abrupt, often severe, and it can become chronic.

What is the medical term for dancing eyes?

Opsoclonus-myoclonus syndrome (OMS), also known as dancing eye syndrome (DES), is a rare neurological condition which develops over days or weeks in early childhood.

How do you treat an OMS?

There are no official treatment recommendations for OMS. Management may involve: Surgery, chemotherapy, and/or radiation: When there is a tumor present, treatment such as surgery for tumor removal, chemotherapy, or radiation may be required.

What is the difference between opsoclonus and nystagmus?

Opsoclonus must be differentiated from nystagmus (rapid jerks followed by a slow corrective saccade) and ocular flutter (horizontal back-to-back saccades). Frequently, generalised myoclonus and ataxia coexist; hence, the term opsoclonus-myoclonus-ataxia.

Is opsoclonus curable?

Although a person may fully recover from the underlying cause of OMS, many people continue to have some neurological impairment. Full recovery is more common in cases due to infection than those due to neuroblastoma. Children with the mildest symptoms have the greatest chance of returning to normal after treatment.

Is opsoclonus myoclonus an autoimmune disorder?

Opsoclonus-myoclonus syndrome (OMS) is a rare autoimmune condition that usually affects young children.

What causes dancing eyes in babies?

Causes. The cause of dancing eye syndrome is not known with certainty but it is thought to be an auto-immune condition. In autoimmune conditions, antibodies which are normally directed to repelling infections and foreign material introduced into the body, start acting against the body itself causing harm.

What is OMS and neuroblastoma?

In OMS, a small tumor in the body (called a neuroblastoma) or a viral infection triggers the immune system to attack the nervous system. The symptoms of OMS usually begin abruptly and can include rapid, repeated eye movements (opsoclonus or “dancing eyes”), jerking movements (myoclonus), and loss of balance (ataxia).

How do you get OMS?

The onset of OMS is usually abrupt and often severe. The disease may become chronic. OMS typically occurs in association with tumors (neuroblastomas), or following a viral or bacterial infection.

What is the fast phase of nystagmus?

In a peripheral vestibular lesion, the fast phase of the nystagmus is usually directed away from the side of a destructive lesion. One can remember this by recalling that cold water in the ear, which causes ipsilateral vestibular dysfunction, produces nystagmus to the opposite side (“cows”) (see Chapter 2).

What kind of disease is dancing eyes dancing feet?

Opsomyoclonus (OMS), also known as dancing eyes-dancing feet syndrome and opsoclonus-myoclonus syndrome, is a clinical syndrome which has a strong association with neuroblastoma.

What does dancing eye syndrome ( DES ) stand for?

Opsoclonus Myoclonus Syndrome/Dancing Eye syndrome (OMS/DES) Opsoclonus-myoclonus syndrome (OMS), also known as dancing eye syndrome (DES), is a rare neurological condition which develops over days or weeks in early childhood.

What is the clinical presentation of a neuroblastoma?

Clinical presentation. The “opso-“ refers to the presence of intermittent jerky eye movements (dancing eyes) and the “myoclonus” to myoclonic jerks and cerebellar ataxia (dancing feet). Although only 2% of patients with neuroblastoma present with opsomyoclonus, up to 50% of patients with opsomyoclonus are ultimately found to have a neuroblastoma 1.

What are the symptoms of opsoclonus dancing eye syndrome?

Unsteadiness (ataxia) and muscle jerks affecting all or some areas of the body are usually the first symptom to appear. Muscle tone seems to decrease causing floppiness and lethargy (tiredness). Behavioural problems, irritability and sleep disturbance are also present.