What is collagen type 1 C-telopeptide?

Collagen Type I C-Telopeptide (CTx) – CTx is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss.

What does high C-telopeptide mean?

Elevated levels of C-terminal telopeptide indicate increased bone turnover. Elevated levels are found in osteoporosis patients with elevated bone turnover who are at increased risk for rapid disease progression.

What is telopeptide in blood test?

This test is used to assess the loss of bone mass (bone resorption) in cases of osteoporosis or other bone diseases such as Paget’s disease.

What is C-telopeptide test for?

What is Type 1 collagen best?

Type 1 Collagen: Minimize fine lines and wrinkles and improves skin elasticity and hydration. Not only does it help rebuild your muscles, eyes, bones, and spine, it’s also good for strengthening your nails and helping you grow stronger, thicker hair. Type 1 collagen is most abundant in Marine Collagen.

How is the C-terminal telopeptide of Type 1 collagen measured?

Measurement of C-terminal telopeptide of type I collagen (CTX) in serum Serum CTX assays measure a fragment of the C-terminal telopeptide of type 1 collagen released during resorption of mature bone. Assay reagents are available in manual and automated formats and give good analytical performance.

Why do you need a blood test for C-telopeptide?

Throughout our lives, old bone is constantly being removed (resorption) and replaced with new bone (formation) to maintain a healthy bone structure. The blood test for C-telopeptide assesses the rate of bone turnover, which can be particularly useful for older individuals.

Is there a C terminal telopeptide for bone resorption?

The cross-linked C-terminal telopeptide of type I collagen, or CTX-I, is a sensitive but also rather variable marker of bone resorption, and several assays for the cross-linked telopeptide are commercially available.

Where is lysine found in a type I collagen telopeptide?

In the carboxy-terminal telopeptides of type I collagen, lysine/hydroxylysine is only present in the α1 (I) chains, making the number of possible alternative cross-linked structures smaller than the corresponding number at the amino-terminus where both α1 (I) and α2 (I) contain lysine/hydroxylysine.