What is Chondroblastic osteosarcoma?

Chondroblastic osteosarcoma is a subtype of osteosarcoma, characterized by the production of chondroid matrix of variable cellularity, most commonly high-grade hyaline cartilage.

What is the survival rate of osteosarcoma?

Osteosarcoma 5-year relative survival rates

Which osteosarcoma has best prognosis?

As for tumor location, several studies have reported the consistent conclusion that osteosarcomas of the extremities have a better survival than the axial osteosarcomas [12,13].

Is metastatic osteosarcoma curable?

Metastatic osteosarcoma These cancers are harder to treat, but some can be cured if the metastases can be removed by surgery. The cure rate for these cancers improves markedly if chemotherapy is also given.

What is the difference between osteosarcoma and osteoma?

Osteosarcoma is larger than osteoid osteoma, exhibits a poorly defined margin radiographically, and microscopically demonstrates greater cytologic atypia and mitoses.

How long can you live with metastatic osteosarcoma?

Five years overall survival in osteosarcoma patients is around 70%, although in patients with metastatic disease it is only 10-30%. The objective of this study was to analyze overall survival and prognostic factors in a group of patients with metastatic osteosarcoma treated with surgical removal of the lung metastases.

Is chemotherapy Effective for osteosarcoma?

The drugs are usually given into a vein and can reach and destroy cancer cells throughout the body. Chemo is an important part of the treatment for most people with osteosarcoma (although some patients with low-grade osteosarcoma might not need it).

Does osteosarcoma run in families?

The cause of osteosarcoma is not known. In some cases, it runs in families, and at least one gene has been linked to increased risk. Treatment varies from person to person and may include surgery, chemotherapy , radiation therapy , and samarium.

How is osteosarcoma treated in the United States?

Treatment for osteosarcoma has greatly improved over the years. The outlook (prognosis) and treatment decisions depend on where the osteosarcoma starts, tumor size, the type and grade of osteosarcoma, and whether the cancer has spread. After completion of treatment, people need lifelong monitoring for potential late effects of intense chemotherapy.

What kind of chemotherapy is used for bone sarcoma?

Treatment of high-grade localized osteosarcoma of the extremity serves as the prototype for the treatment of most bone sarcomas and consists of neoadjuvant chemotherapy followed by limb-sparing surgical resection and subsequent adjuvant chemotherapy.

How long do you take chemotherapy for osteosarcoma?

Most osteosarcomas are treated with chemo before surgery (known as neoadjuvant chemotherapy) for about 10 weeks. In some people with osteosarcoma in an arm or leg bone, this can shrink the tumor, which might help make surgery easier.

Where does osteosarcoma usually occur in the body?

Osteosarcoma is most often found in the long bones — more often the legs, but sometimes the arms — but it can start in any bone. Osteosarcoma tends to occur in teenagers and young adults, but it can also occur in younger children and older adults. Treatment usually involves chemotherapy and surgery.