What is a Glycoconjugate vaccine?

Glycoconjugate vaccines use protein carriers to improve the immune response to polysaccharide antigens. The protein component allows the vaccine to interact with T cells, providing a stronger and longer-lasting immune response than a polysaccharide interacting with B cells alone.

What is meningococcal polysaccharide vaccine for?

Meningococcal polysaccharide diphtheria conjugate vaccine is an active immunizing agent used to prevent infection by certain groups of meningococcal bacteria. The vaccine works by causing your body to produce its own protection (antibodies) against the bacteria.

Who should get meningococcal conjugate vaccine?

CDC recommends routine MenACWY vaccination for: All preteens and teens at 11 to 12 years old with a booster dose at 16 years old. Children and adults at increased risk for meningococcal disease.

What is meningococcal Acwy vaccine?

The MenACWY vaccine is given by a single injection into the upper arm and protects against 4 strains of the meningococcal bacteria – A, C, W and Y – which cause meningitis and blood poisoning (septicaemia). The MenACWY vaccine is called Nimenrix.

How do Glycoconjugate vaccines work?

Is peptidoglycan a Glycoconjugate?

Glycoconjugates are formed in processes termed glycosylation. Glycoconjugates are very important compounds in biology and consist of many different categories such as glycoproteins, glycopeptides, peptidoglycans, glycolipids, glycosides, and lipopolysaccharides.

What is the difference between conjugate and polysaccharide vaccines?

In the polysaccharide vaccine, only the sugar part of the bacteria, the capsule, is included as the antigen to stimulate the immune response. “In the conjugate vaccine, it’s actually the sugar joined to the carrier protein,” says Associate Professor Kristine Macartney.

Is meningococcal Acwy the same as MCV4?

A3: One dose of meningococcal conjugate vaccine (MenACWY; sometimes abbreviated as MCV4; brand names Menactra or Menveo) is required for entry into grades 7 through 11.

Is meningococcal C the same as meningococcal Acwy?

This vaccine protects against meningococcal disease caused by serogroups A, C, W and Y. This dose of MenACWY vaccine replaced the combined Haemophilus influenza type b–meningococcal C conjugate (Hib-MenC) vaccine (Menitorix®) given at 12 months of age which only covered serogroup C.

Which of the following are vaccine Stabilisers?

Stabilisers Examples of additives include lactose and sucrose (both sugars), glycine and monosodium glutamate (both of which are amino acids or salts of amino acids), and human or bovine (cow) serum albumin (both proteins).