What is a commonly prescribed thiazide diuretic?
What are thiazide diuretics? Hydrochlorothiazide, chlorothiazide, and metolazone are some examples of thiazide diuretics that treat high blood pressure and fluid retention.
What is an example of a thiazide-like diuretic?
Thiazide-type diuretics include chlorothiazide, HCTZ, methychlothiazide, trichlormethiazide, polythiazide, bendroflumethiazide and thiazide-like diuretics include indapamide, CTDN, and metolazone.
When are thiazide diuretics used?
Thiazide diuretics are mainly used to treat high blood pressure (hypertension). They are occasionally also used for heart failure. When used to treat heart failure they are often combined with another type of medicine called a loop diuretic.
Which thiazide diuretic is best?
Hydrochlorothiazide (HCTZ) and chlorthalidone are both thiazide diuretics recommended as first-choice options for treating high blood pressure because of their benefits on heart health and overall death rates.
Are thiazide diuretics safe?
Diuretics are generally safe. Side effects include increased urination and sodium loss. Diuretics can also affect blood potassium levels. If you take a thiazide diuretic, your potassium level can drop too low (hypokalemia), which can cause life-threatening problems with your heartbeat.
What is the difference between thiazide and hydrochlorothiazide?
Key points. HCTZ is less potent than other thiazide diuretics, including CTD and bendroflumethiazide in lowering BP, at the lower dose range of 12.5–25 mg daily.
What do thiazide diuretics act on?
Thiazide diuretics work by blocking sodium and chloride (Na/Cl) channels in the distal convoluted tubule of the nephron and inhibit the reabsorption of sodium and water. This also causes a loss of potassium and calcium ions.
What does a thiazide diuretic do?
Thiazide diuretics are an FDA-approved class of drugs that inhibit reabsorption of 3% to 5% of luminal sodium in the distal convoluted tubule of the nephron. By doing so, thiazide diuretics promote natriuresis and diuresis.
What does thiazide do to urine?
Thiazides increase urine output by inhibiting the NaCl cotransporter on the luminal membrane of the earliest portion of the distal convoluted tubule, often called the cortical diluting segment (Fig. 9-5).
How long does it take thiazide to work?
The onset of action occurs after 2 to 3 hours for most thiazides, with little natriuretic effect occuring beyond 6 hours (2).
How does a thiazide diuretic work?
What is the most common diuretic?
The two most commonly prescribed diuretics in the United States are Furosemide ( lasix) and hydrochlorothiazide. Generally speaking, hydrochlorothiazide is used more for blood pressure control and Lasix (furosemide) is used more for treatment of congestive heart failure.
What is the best supplement for water retention?
Certain dietary supplements may help treat your water retention. To help treat edema, you might take supplements of omega-3 fatty acids like fish oil, magnesium, alpha-lipoic acid or vitamin C, according to the UMMC.
Is thiazide a sulfa drug?
Sulfonamide (medicine) Hydrochlorothiazide is a sulfonamide and a thiazide. Furosemide is a sulfonamide, but not a thiazide. Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs.
Do diuretics affect sodium and potassium levels?
The filtering of blood through your kidneys maintains the chemical balance of the blood, including the potassium and sodium levels. Diuretics cause the kidneys to put more sodium into the blood, thus pulling more fluid out of the interstitial tissues and excreting more fluid into the urine.
