What does CAM5 2 positive mean?

The monoclonal antibody CAM5. 2 was typically used to identify secretory epithelial (glandular epithelium) cells and epithelial tumors, such as colorectal cancer and pancreatic cancer. Additionally, CAM5. 2 is generally accepted to be suitable for detection of metastatic breast cancer in (sentinel) lymph nodes.

What does CAM 5. 2 stain for?

CAM 5.2 stains most epithelial derived tissue, including liver, renal tubular epithelium, hepatocellular and renal cell carcinomas. CAM 5.2 may not react with some squamous cell carcinomas.

What is Pan cytokeratin?

Product Description. Pan Cytokeratin [AE1/AE3] antibody recognizes the acidic and basic (Type I and II) subfamilies of cytokeratins. The cocktail of these two antibodies has been shown to detect in human epithelia. The acidic cytokeratins have molecular weights of 56.5, 55, 51, 50, 50, 48 46, 45 and 40 kDa.

What does KI 67 stand for?

The Ki-67 percentage score is defined as the percentage of positively stained tumor cells among the total number of malignant cells assessed [11]. Withal only the positivity is of interest independent of the intensity of coloration. To ensure quality assurance of the staining, positive control tissues are completed.

What CK20 positive?

For example, a CK7-negative/CK20-positive phenotype is often associated with carcinomas of colorectal origin, whereas a CK7-positive/CK20-negative phenotype is seen in a wide variety of carcinomas, including carcinomas of the lung, breast, thyroid, pancreas, and female genital tract.

Are histiocytes vimentin positive?

Lysozyme, vimentin, and CD68 were positive in all cases with histological information.

What does cytokeratin positive mean?

Cytokeratin 5/6 is a positive marker for malignant pleural mesothelioma, found in more than three-fourths of cases. It is also found in certain types of lung cancers and breast cancers.

Is cytokeratin an antibody?

Cytokeratin pan antibody is an antibody cocktail mixture that can detect multiple cytokeratins and reacts to multiple epithelial tissues (1,3,6).

What tumors are CK7 positive?

Metastatic Tumors to Skin CK7 is often positive in upper gastrointestinal tract tumors such as gastric and duodenal carcinoma. Colonic carcinomas, in contrast, are typically CK7(-)/CK20(+). This is metastatic gastric carcinoma, which first presented as a skin metastasis in an older adult patient.