What causes hepatocellular injury?

Hepatitis A, hepatitis B and hepatitis E can cause acute liver failure. Other viruses that can cause acute liver failure include Epstein-Barr virus, cytomegalovirus and herpes simplex virus. Toxins.

What causes the liver to be injured?

Most liver injuries are caused by blunt trauma from motor vehicle crashes, falls, bicycle crashes, violence, or by a penetrating injury that tears or cuts the liver.

What does the liver do?

Functions of the liver All the blood leaving the stomach and intestines passes through the liver. The liver processes this blood and breaks down, balances, and creates the nutrients and also metabolizes drugs into forms that are easier to use for the rest of the body or that are nontoxic.

What are the two main patterns of liver injury?

The two main patterns of liver injury are hepatocellular (main injury as the hepatocyte level) and cholestatic (main injury at any level of the biliary excretory system). Liver cell necrosis will lead to a hepatocellular injury pattern.

What does liver injury mean?

A liver injury, also known as liver laceration, is some form of trauma sustained to the liver. This can occur through either a blunt force such as a car accident, or a penetrating foreign object such as a knife. Liver injuries constitute 5% of all traumas, making it the most common abdominal injury.

Which laboratory elevations are associated with hepatocellular injury?

Introduction. The differential diagnosis of marked aminotransferase elevations (more than 15 times the upper limit of normal) is quite limited. This degree of elevation is generally associated with massive hepatocellular injury and/or necrosis.

What does hepatocellular mean?

Hepatocellular disease is a type of liver disease. With hepatocellular disease, the liver is usually inflamed and will show signs of injury to the liver.

What is hepatocellular damage?

Hepatocellular damage occurs when Hepatocyte cells are affected in the liver. These cells make up 70 to 80 per cent of the cytoplasmic mass of the liver. Cytoplasm is a thick liquid which exists between the cell membrane that holds the organelles, which are a sub unit within a cell. Hepatocyte cells help to perform several different functions.

What is hepatocellular dysfunction?

Hepatocellular dysfunction is a very broad term and does not indicate a specific disease. It means liver diseases like cirrhosis, hepatitis and fatty liver. Since there is history of hepatitis C infection from a long time, that could be possible cause of your symptoms.

What is toxic liver disease, or hepatotoxicity?

What is toxic liver disease? Toxic liver disease is damage to your liver. It’s also called hepatotoxicity or toxic hepatitis. It can cause serious symptoms or liver damage if you don’t get help. Medications, herbal supplements, chemicals, solvents, and alcohol are all possible causes of hepatotoxicity.