What can you not take with colchicine?

What drugs and food should I avoid while taking Colchicine (Colcrys)? Grapefruit and grapefruit juice may interact with colchicine and lead to unwanted side effects. Avoid the use of grapefruit products while taking colchicine.

Does colchicine affect the liver?

Introduction. Colchicine is a plant alkaloid that is widely used for treatment of gout. Colchicine has not been associated with acute liver injury or liver test abnormalities except with serious overdoses.

Is colcrys safe?

Colchicine may rarely cause a certain serious (even fatal) muscle damage (rhabdomyolysis). This muscle damage releases substances that can lead to serious kidney problems. The risk may be increased if other drugs that may also cause rhabdomyolysis are taken along with colchicine.

What is the most common side effect of colchicine?

Gastrointestinal disorders are the most common adverse reactions with colchicine. They are often the first signs of toxicity and may indicate that the colchicine dose needs to be reduced or therapy stopped. These include diarrhea, nausea, vomiting, and abdominal pain.

Is colcrys bad for kidneys?

Colchicine is excreted renally and can accumulate to toxic levels in renal impairment. Colchicine is not contraindicated, but dose adjustment and close monitoring is suggested. Signs of toxicity include leukopenia, elevation of aspartate aminotransferase, and neuropathy.

What are the long-term side effects of colchicine?

Serious side effects of colchicine

  • Myelosuppression (decreased bone marrow activity)
  • Leukopenia (reduced white blood cells)
  • Thrombocytopenia (reduced platelets)
  • Granulocytopenia (reduced granulocytes)
  • Pancytopenia (reduced red blood cells)
  • Aplastic anemia.
  • Severe diarrhea.
  • Myopathy (disease of muscle tissue)

Is colcrys bad for your kidneys?

Is colcrys a steroid?

Colchicine is an anti-inflammatory, immuno modulating agent, which could potentially have a beneficial effect in the treatment of asthma as well as act as a steroid-sparing agent.

What are the long term side effects of colchicine?

How should I take Colcrys?

Take Colcrys exactly as your healthcare provider tells you to take it.

  • Colcrys can be taken with or without food.
  • If you take too much Colcrys,go to the nearest hospital emergency room right away.
  • Do not stop taking Colcrys even if you start to feel better,unless your healthcare provider tells you.

    • What are the most common drug interactions?

    The three primary types of drug interactions are pharmaceutical, pharmacodynamic, and pharmacokinetic. Metabolic interactions are the most common, but other types of interactions can occur in patients undergoing chemotherapy.

    How long to take Colcrys?

    COLCRYS may be administered for treatment of a gout flare during prophylaxis at doses not to exceed 1.2 mg (two tablets) at the first sign of the flare followed by 0.6 mg (one tablet) one hour later. Wait 12 hours and then resume the prophylactic dose.

    Can azithromycin interfere with Cordarone?

    Azithromycin ( Zithromax ®) is one of the drugs that can interfere with Cordarone. Combining Cordarone with azithromycin may increase the risk for potentially serious heart rhythm problems. If you must use these medicines together, your healthcare provider will need to closely monitor you.