What are the side effects of cyclophosphamide?
Cyclophosphamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea.
- vomiting.
- loss of appetite or weight.
- abdominal pain.
- diarrhea.
- hair loss.
- sores on the mouth or tongue.
- changes in skin color.
Is cyclophosphamide toxic?
Clinically, damage to the bladder (haemorrhagic cystitis), immunosuppression (when not desired) and alopecia are the most significant toxicities associated with cyclophosphamide. Cardiotoxicity is also a possibility when very high doses are given.
Can you touch cyclophosphamide?
Wear gloves when touching this medicine (cyclophosphamide capsules). Swallow whole. Do not chew, break, or crush. Do not open the capsules.
What type of chemo is cyclophosphamide?
Drug Type: Cyclophosphamide is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “alkylating agent.” (For more detail, see “How Cyclophosphamide Works” section below).
How much water should I drink with cyclophosphamide?
Follow your doctor’s instructions carefully about how much fluid to drink every day. Some patients may have to drink up to 7 to 12 cups (3 quarts) of fluid a day. Usually it is best to take cyclophosphamide first thing in the morning, to reduce the risk of bladder problems.
What is cyclophosphamide oral?
Cyclophosphamide is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cell growth. Cyclophosphamide also works by decreasing your immune system’s response to various diseases.
What is the most common side effect of cyclophosphamide?
Nausea, vomiting, loss of appetite, stomach ache, diarrhea, or darkening of the skin/nails may occur. Nausea and vomiting can be severe. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting.
Does cyclophosphamide have a boxed warning?
No. Cycrame does not have any specific boxed warning. Please discuss with your doctor about all the possible side effects and warnings relating to use of Cycrame The information given above is for Cyclophosphamide which is the active ingredient of Cycrame.
What is the mechanism of cyclophosphamide?
Cyclophosphamide is biotransformed principally in the liver to active alkylating metabolites by a mixed function microsomal oxidase system. These metabolites interfere with the growth of susceptible rapidly proliferating malignant cells. The mechanism of action is thought to involve cross-linking of tumor cell DNA.
How does cyclophosphamide work?
Cyclophosphamide works by stopping the cancer cells from multiplying. It does this by binding to and damaging the DNA in the cancer cells. This stops the cells from growing and multiplying. Cyclophosphamide is used in the treatment of a wide variety of cancers including cancer of the lymph nodes (lymphoma) and blood cells (leukaemias).
