What are the normal parameters of synovial fluid analysis?
Normal constituents of the synovial fluid:
| Features | |
|---|---|
| Glucose | <10 mg/dL lower than the blood level |
| Total protein | <3 G/dL (1 to 3 G/dL) |
| Lactate | <250 mg/dL |
| Uric acid | This is equal to the blood level (male = 2 to 8mg/dL and female = 2 to 6 mg/dL) |
What is the normal appearance of synovial fluid?
In normal conditions, synovial fluid is colorless or faint yellow and clear, and it can form viscous strings of 4-6 cm (owing to polymerization of hyaluronic acid).
What color is normal synovial fluid?
Normal synovial fluid is straw-colored, clear, and slightly sticky or stringy. Abnormal synovial fluid may be cloudy and thicker or thinner than normal fluid. Cloudiness could mean there are crystals, excess white blood cells, or microorganisms in the fluid. If you have gout, the fluid will contain crystals.
What does high WBC in synovial fluid mean?
The synovial fluid may be cloudy or thick. A high white blood cell count could mean you have an infection or another medical condition. A high uric acid level and crystals could signal gout.
What is the normal range of glucose in synovial fluid?
Synovial fluid glucose is normally within 10 mg/dL of plasma glucose. Neither synovial fluid glucose nor protein provides much useful diagnostic information. White cell counts (WBC) are normally less than 200/uL with fewer than 25% neutrophils.
What is a normal nucleated cell count in synovial fluid?
In a recent study, smears of normal synovial fluid revealed one to three nucleated cells per high-power field (HPF) (100× oil-immersion objective). Each nucleated cell per HPF was equivalent to 1000 cells per milliliter. Less than 10% of the nucleated cells in normal synovial fluid are neutrophils,.
What color is infected synovial fluid?
Normal synovial fluid is clear and colorless or straw-colored. Abnormal fluid may look cloudy, opaque, and/or differently colored. For example, cloudy fluid may indicate an infection, and pink or reddish fluid may indicate the presence of blood.
Why is my synovial fluid yellow?
Normal synovial fluid is clear in color, transparent in clarity, and highly viscous. Therefore, fluid that is yellow/green, opaque, and very thin is more likely to represent a septic joint.
What is a good total nucleated cell count?
Parent’s Guide to Cord Blood (PGCB) says the median number of total nucleated cells in a 60 mL cord blood collection is 47.0 x 107, or 470 million cells. The minimum accepted public donation is often closer to one billion cells.
What is the normal cell count and predominant cell type in synovial fluid?
Smear assessment: Normal joint fluid is viscous and of low cellularity. Cells are comprised of 50-90% mononuclear cells, of which 80% or more are macrophages or synovial lining cells with <20% lymphocytes. There are usually <10% neutrophils (non-degenerate).
