How is radium-223 administered?
Radium-223 dichloride is given through a vein (intravenously, IV), as a slow [intravenous] injection, over about 1 minute. There is no pill form of radium-223 dichloride. It is given in a clinic or facility where healthcare providers or technicians have been trained to give radiation therapy.
Is Xofigo FDA approved?
The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs.
What is Xofigo used to treat?
Xofigo is a medication used to treat prostate cancer that has spread to your bone.
How long does radium-223 extend life?
Evidence sinthesis: According to the ALSYMPCA study, Radium 223 significantly prolongs the overall survival of patients with castration resistant prostate cancer and bone metastases; approximately 3.6 months in comparison with patients who received placebo, which turns into a median life expectancy of 14.9 months, and …
How effective is Xofigo?
Effectiveness for prostate cancer In this study: those treated with Xofigo were 30% less likely to die than those treated with a placebo (a treatment containing no active drug) at least 50% of those treated with Xofigo lived for 14.9 months. at least 50% of those treated with a placebo lived for 11.3 months.
How long does it take for Xofigo to work?
Xofigo is absorbed into your bones, and the radiation kills the cancer cells there. Xofigo comes as a liquid solution in single-dose vials. Your healthcare provider will administer this medication by injection into your vein. This takes about 1 minute.
Is Xofigo radiation therapy?
Xofigo is a radioactive targeted therapy. This means that it has 2 main parts: a radioactive part and a tumor-targeted part. The tumor-targeted part helps the medication fight just the tumor cells, not your normal cells. This helps keep the medication from damaging healthy parts of your body.
How long does radium 223 extend life?