How did Linus Pauling discover the structure of DNA?
Pauling and Corey conclude the first part of “Nucleic Acids” with a brief mention of DNA, specifically X-ray diffraction patterns of DNA. They cite scientists who obtained X-ray diffraction images of DNA, including Astbury at the University of Leeds.
Which type of enzyme catalyses the synthesis of DNA?
The process of DNA replication is catalyzed by a type of enzyme called DNA polymerase (poly meaning many, mer meaning pieces, and –ase meaning enzyme; so an enzyme that attaches many pieces of DNA).
What is the simplified structure of DNA?
DNA is made up of molecules called nucleotides. Each nucleotide contains a phosphate group, a sugar group and a nitrogen base. The four types of nitrogen bases are adenine (A), thymine (T), guanine (G) and cytosine (C).
What was wrong with Linus Pauling’s DNA model?
This is Linus Pauling’s failed attempt to predict the structure of DNA. The problem with his triple helix model is that the phosphates form the helical core, with the bases pointing outwards. This would be impossible under normal cellular conditions.
What did Pauling and Corley suggest DNA looked like?
Pauling hypothesized that DNA was likely helical in shape, with the large base groups facing out and the phosphate groups stacked in the core.
Why is complementary base pairing important in DNA structure?
Hint: Complementary base pairing is very important in DNA molecule because it allows the base pairs to be arranged in the more energetically favourable way. it is essential in forming the double-helical structure of DNA. It is also important in replication of DNA as it allows semiconservative replication.
What protects Unreplicated DNA?
Newly-exposed, unreplicated DNA is protected by single-strand binding protein. Short segments of RNA are synthesized, called RNA primers.
What is the name of the enzyme that unzips DNA?
During DNA replication, DNA helicases unwind DNA at positions called origins where synthesis will be initiated. DNA helicase continues to unwind the DNA forming a structure called the replication fork, which is named for the forked appearance of the two strands of DNA as they are unzipped apart.
What are the 4 bases of DNA?
There are four nucleotides, or bases, in DNA: adenine (A), cytosine (C), guanine (G), and thymine (T). These bases form specific pairs (A with T, and G with C).