Does Pfizer make vincristine?

Vincristine is a critical therapy in the treatment of cancer and is often used in the treatment of childhood cancers. Pfizer is committed to the manufacture of this medicine and to reliably supplying it to patients who need it.

Why is vincristine only given IV?

For IV use only: Vincristine is indicated for IV use only. It is fatal if given by any other routes. Vincristine administered by intrathecal routes usually results in death.

How do you administer vincristine?

Vincristine sulfate is administered by intravenous infusion at weekly intervals. Great care should be exercised in calculating and administering the dose as overdosage may be extremely serious or even fatal.

What is the brand name of vincristine?

Oncovin and Vincasar Pfs are trade names for Vincristine.

Why is vincristine being discontinued?

It is ramping up production of vincristine—often used with other drugs to treat leukemia, brain tumors and lymphomas—after Teva in July notified the FDA that it had made the “business decision” to discontinue production. Its move has left pediatric oncologists scrambling to find supplies.

Is vincristine a strong chemo drug?

Vincristine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. Vincristine is classified as a plant alkaloid.

Is vincristine a chemo drug?

Vincristine is used to treat various types of cancer. It is a cancer chemotherapy drug that is usually used with other chemotherapy drugs to slow or stop cancer cell growth.

Can you kiss a chemo patient?

Kissing is a wonderful way to maintain closeness with those you love and is usually okay. However, during chemotherapy and for a short time afterward, avoid open-mouth kissing where saliva is exchanged because your saliva may contain chemotherapy drugs.

What are the side effects of vincristine?

Vincristine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea.
  • vomiting.
  • sores in the mouth and throat.
  • loss of appetite or weight.
  • stomach pain.
  • diarrhea.
  • headache.
  • hair loss.

How to prepare for the injection of vincristine sulfate?

Caution–This preparation should be administered by individuals experienced in the administration of Vincristine Sulfate Injection, USP. It is extremely important that the intravenous needle or catheter be properly positioned before any vincristine is injected.

What kind of cancer can vincristine sulfate be used for?

Vincristine sulfate injection is indicated in acute leukemia. Vincristine sulfate injection has also been shown to be useful in combination with other oncolytic agents. in Hodgkin’s disease, non–Hodgkin’s malignant lymphomas, rhabdomyosarcoma, neuroblastoma, and. Wilms’ tumor.

What is the formula for vincristine sulfate, USP?

The molecular formula for Vincristine Sulfate, USP is C46H56N4O10∙H2SO4. It has a molecular weight of 923.04. The structural formula is as follows: Vincristine Sulfate, USP is a white to off–white powder. It is soluble in methanol, freely soluble in water, but only slightly soluble in 95% ethanol.

What is the ultraviolet spectrum of vincristine sulfate?

In 98% ethanol, Vincristine Sulfate, USP has an ultraviolet spectrum with maxima at 221 nm (∈+47,100). Vincristine Sulfate Injection, USP is a sterile, preservative–free, single-dose only solution available for intravenous use in 2 mL (1 mg and 2 mg) vials.