Can HSIL be misdiagnosed?

Differential Diagnosis Conditions that can be mistaken for HSIL on biopsy include early invasive carcinoma, atrophy, squamous metaplasia, transitional metaplasia and reactive atypia.

What percentage of HSIL is cancer?

HSIL. CIN 2 or CIN 3 has been reported in at least 70 percent of women with cytology results of high-grade squamous intraepithelial lesions (HSIL), and 1 to 2 percent have invasive cancer.

Can you see cervical cancer on colposcopy?

Very rarely, some women are found to have cervical cancer during a colposcopy. If you have cancer, you’ll be quickly referred to a specialist team for care and treatment. As cervical cancer detected through screening tends to be diagnosed at an early stage, the outcome of treatment tends to be better.

Can HSIL be false positive?

A false positive screening result was defined as an index test classified as high-grade cytological abnormalities (ASC-H, AGC, HSIL+) with a subsequent ≤ CIN1 cervical biopsy result within the next 6 months.

What does HSIL mean on a Pap smear?

High-Grade Squamous Intraepithelial Lesions (HSIL) means that there are moderately or severely abnormal cervical cells that could become cancer in the future if not treated. Your health care provider will likely ask you to come back for a colposcopy.

How often does HSIL turn into cervical cancer?

The risk that HSIL abnormalities signify precancerous changes is as high as 53 percent, and the risk of cervical cancer is as high as 7 percent [1,2].

Should I be worried about HSIL?

HSIL suggests more serious changes in the cervix than LSIL. It is more likely than LSIL to be associated with pre-cancer and cancer. ASC-H means that changes in the cervical cells have been found that raise concern for the presence of HSIL.

Can a doctor tell if you have cancer during a colposcopy?

A pathologist can identify abnormal cells by looking at the tissue sample under a microscope. While a colposcopy can suggest that you have cancer or precancerous tissue, only a biopsy can actually make a diagnosis.

How many Lletz can you have?

How many times can you have the LLETZ procedure, can you have LLETZ twice? Mr John Butler explains that most women will only need one LLETZ procedure. However, if abnormal cells come back, you may require further procedures, and this is perfectly safe and acceptable.

Can colposcopy results be wrong?

About 6 in 10 colposcopy results are abnormal. This means the tests done during colposcopy or biopsy have confirmed you have cell changes. Possible abnormal results include: cervical intraepithelial neoplasia (CIN)