What drug class is terconazole?

Terconazole is an anti-fungal drug that is mainly used to treat vaginal yeast infections (or vaginal candidiasis). It is classified as a triazole ketal derivative.

Is terconazole radioactive?

Terconazole is extensively metabolized; the plasma AUC for terconazole compared to the AUC for total radioactivity was 0.6%. Total radioactivity was eliminated from the blood with a harmonic half-life of 52.2 hours (range 44-60). Excretion of radioactivity was both by renal (32-56%) and fecal (47-52%) routes.

What happens if you use terconazole?

Terconazole reduces vaginal burning, itching, and discharge that may occur with this condition. This medication is an azole antifungal. It works by stopping the growth of yeast (fungus) that causes the infection.

How long does it take for terconazole to leave your system?

Elimination. Across various studies in healthy women, after single or multiple intravaginal administration of terconazole as the cream or suppository/ovule, the mean elimination half-life of unchanged terconazole ranged from 6.4 to 8.5 hours.

Is terconazole an antibiotic?

Terconazole is an antifungal medication that fights infections caused by fungus.

Is terconazole used for BV?

Terconazole is only effective for vaginal infections caused by a species of yeast called Candida. It is not effective for other infections, such as bacterial vaginosis.

Is terconazole an imidazole?

Terconazole is a new broad-spectrum antifungal agent for the treatment of vulvovaginal candidiasis. Instead of an imidazole structure, terconazole contains a triazole ring, a structure developed specifically to improve antifungal activity.

Is terconazole supposed to burn?

SIDE EFFECTS: Headache, increased vaginal/urethral burning/itching/pain, or menstrual cramps may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Is it normal for terconazole to come out?

This medicine may leak out of your vagina during the day. You may wear a sanitary pad to protect your clothing, but do not use a tampon. Keep using this medicine for the full time of treatment, even if your symptoms improve after the first few doses.

Does terconazole cream affect birth control?

Terconazole vaginal suppositories contain ingredients that can damage a diaphragm. You should not use this form of birth control during treatment with terconazole vaginal suppositories.

Do you have to use terconazole at night?

Terconazole comes as a cream and suppository to insert into the vagina. It is usually used daily at bedtime for either 3 or 7 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use terconazole exactly as directed.

Can sperm give you yeast infections?

Vaginal Sex But sometimes sexual activity can lead to vaginitis. Your partner’s natural genital chemistry can change the balance of yeast and bacteria in your vagina. In rare cases, you can have an allergic reaction to your partner’s semen.

When to use terconazole 0.8% vaginal cream?

During controlled clinical studies conducted in the United States, patients with vulvovaginal candidiasis were treated with terconazole 0.8% vaginal cream for three days.

What are the side effects of terconazole 3 day cream?

Genital complaints in general, and burning and itching in particular, occurred less frequently in the terconazole 0.8% vaginal cream 3 day regimen (5% vs. 6%-9% with placebo). Other adverse experiences reported with terconazole 0.8% vaginal cream were abdominal pain (3.4% vs. 1% with placebo) and fever (1% vs. 0.3% with placebo).

What’s the difference between terazol 3 and terconazole 7?

It is insoluble in water; sparingly soluble in ethanol; and soluble in butanol. TERAZOL® 7 (terconazole) Vaginal Cream 0.4%, TERAZOL® 3 (terconazole) Vaginal Cream 0.8% and TERAZOL® 3 (terconazole) Vaginal Suppositories 80 mg are indicated for the local treatment of vulvovaginal candidiasis (moniliasis).

When does the concentration of terconazole reach maximum?

Maximum plasma concentrations of terconazole occur 5 to 10 hours after intravaginal application of the cream or suppository. Systemic exposure to terconazole is approximately proportional to the applied dose, whether as the cream or suppository.