Is TIPS contraindicated in hepatic encephalopathy?

In recent guidelines, TIPS is not recommended for prevention of rebleeding in patients who have bled only once in the past [1]. Despite its success in eradicating varices, TIPS cannot be recommended in all patients because of the risks of encephalopathy and procedural complications.

What is a TIPS stent made of?

The stent used in this procedure is a small wire mesh tube, often covered with a fabric made of GORE-TEX®. This procedure may use other equipment, including an intravenous line (IV), ultrasound machine and devices that monitor your heart beat and blood pressure.

Does TIPS worsen hepatic encephalopathy?

Hepatic encephalopathy is among the most frequent complications encountered by individuals with end stage liver disease. It is often exacerbated by placement of a TIPS, which involves creation of a shunt, allowing portal blood flow to bypass the liver parenchyma.

When is TIPS indicated?

When is TIPS procedure indicated? TIPS is indicated to treat patients with portal hypertension (variceal bleeding, portal hypertension gastropathy and severe ascites) and in some cases in Budd-Chiari Syndrome.

Where is TIPS inserted?

A TIPS procedure may be done by a radiologist, who places a small wire-mesh coil (stent) into a liver vein. The stent is then expanded using a small inflatable balloon (angioplasty). The stent forms a channel, or shunt, that bypasses the liver. This channel reduces pressure in the portal vein.

How does TIPS increase encephalopathy?

Episodes of hepatic encephalopathy that occur within weeks after TIPS are often induced by specific precipitating factors (eg, dietary protein indiscretion, gastrointestinal bleeding, sepsis, dehydration, hypokalemia, hypoxia, constipation, use of sedatives or psychoactive medications), particularly in patients with …

How is TIPS performed?