What is an oligomeric enzyme?
Oligomeric proteins, by definition, are composed of more than one subunit (polypeptide chain). As such, they possess a quaternary structure, generally considered to be the highest level of organization within the protein structural hierarchy.
What is oligomerization process?
Oligomerization is a chemical process that converts monomers to macromolecular complexes through a finite degree of polymerization. Telomerization is an oligomerization carried out under conditions that result in chain transfer, limiting the size of the oligomers.
What is a dimeric enzyme?
dimer A protein that is made up of two polypeptide chains or subunits paired together. An example of a dimeric enzyme is glucose–phosphate isomerase. Some enzymes are trimeric (comprising three components) or tetrameric (with four components).
What is monomeric and oligomeric enzymes?
(a) Monomeric enzymes: Consist of one polypeptide chain (subunit), e.g., ribonuclease, lysozyme, hexokinase etc. (b) Oligomeric enzymes: Consist of more than one oolypeptide chain. They are functional in their quaternary structure.
Is hemoglobin an oligomeric?
Oligomeric proteins include the hemoglobins, allosteric enzymes responsible for the regulation of metabolism, contractile proteins such as actin and tubulin, and cell membrane proteins.
What causes oligomerization?
Oligomerization is predominantly observed in vitro during crystallization, probably due to the high protein concentration, as well as by other factors like pH or ionic strength of the solution.
What is oligomer example?
For example, oligomers can be nonfunctional, mono functional or multifunctional and be used to enhance performance or environmental properties. Some common oligomer types used in applications in addition to light cure systems include epoxy ester, urethane, epoxy, acrylic, polyester and polycaprolactone.
What are monomeric and oligomeric enzymes give examples?
(a) Monomeric enzymes: Consist of one polypeptide chain (subunit), e.g., ribonuclease, lysozyme, hexokinase etc. (b) Oligomeric enzymes: Consist of more than one oolypeptide chain.