How does PCR detect Ebola?
viruses (Ebola Zaire, Sudan and Reston strains), confirming that they are gene- and strain- specific. The RT-PCR assays detected viral RNAs in blood samples from virus-infected animal, suggesting that they can be also a useful method for identifying Ebola virus in clinical samples.
Is the BioFire a PCR test?
Authorized by the FDA for the point-of-care space under an Emergency Use Authorization, the BioFire RP2. 1-EZ Panel (EUA) identifies a menu of 19 respiratory targets, including SARS-CoV-2, in one multiplex PCR test, with results in about 45 minutes.
What is BioFire technology?
The BioFire System is the new standard for syndromic infectious disease diagnostics. Simple, fast, and comprehensive, the BioFire System delivers accurate results in about one hour. The FDA-cleared BioFire System panels test for viruses, bacteria, parasites, yeast, and antimicrobial resistance genes.
Is Ebola Gram positive or negative?
Ebola virus is a 19-kb, single-strand, negative-sense RNA virus that belongs to the family Filoviridae, order Mononegavirales.
How accurate is the BioFire test?
The agreement between the BioFire COVID-19 test and Quanty COVID-19 assay was 95.0% (114/120) for overall results and 100% (34/34) for negative results.
What class of virus is Ebola?
The Problem. Ebola virus is a class A bioterrorism agent, known to cause highly lethal hemorrhagic fever. The mortality rate can be as high as 90 percent. Because the Ebola virus is so hazardous, it is classified as a biosafety level 4 agent – the level assigned to the most dangerous agents known.
How much does BioFire cost?
The list price on the FilmArray platform is $49,000, although BioFire provides a discount based on the number of systems bought, President and COO Randy Rasmussen said on the conference call. The list price on consumables for the respiratory and GI tests is $129.
How long will a PCR test show positive?
From this point, the amount of virus gradually declines, until it can no longer be detected by PCR. In general, asymptomatic people may test positive for 1-2 weeks, while those with mild-to moderate disease often continue to test positive for a week or more after this.
