How do you give romiplostim injection?

Administer Nplate as a weekly subcutaneous injection with dose adjustments based upon the platelet count response. The prescribed Nplate dose may consist of a very small volume (e.g., 0.15 mL). Administer Nplate only with a syringe that contains 0.01 mL graduations.

What is the difference between romiplostim and eltrombopag?

Romiplostim is a recombinant, Fc-peptide fusion protein (peptibody) given subcutaneously, while eltrombopag is an orally available drug that binds to the transmembrane region of c-MpL [17].

How long does romiplostim take to work?

It may take up to 4 weeks of before Nplate is completely effective in preventing bleeding episodes. Keep receiving the medication as directed. Talk with your doctor if you have any bruising or bleeding episodes after 4 weeks of treatment.

How much does romiplostim cost?

Healthcare practitioners were consulted regarding romiplostim and IVIg treatment algorithms and the resources involved in patient monitoring. Results: The average annual drug acquisition costs of romiplostim and IVIg were $48,024 and $98,868, respectively.

What is romiplostim injection?

ROMIPLOSTIM (roe mi PLOE stim) helps your body make more platelets. This medicine is used to treat low platelets caused by chronic idiopathic thrombocytopenic purpura (ITP). COMMON BRAND NAME(S): Nplate.

Is eltrombopag an immunosuppressant?

We added eltrombopag, a thrombopoietin-receptor agonist, to standard immunosuppressive therapy in patients with previously untreated severe aplastic anemia.

Is romiplostim expensive?

Cost. The current wholesale price of romiplostim is $1,062.50 for a single-use vial of 250 µg or $2,125.00 for a single-use vial of 500 µg. Most patients who respond to romiplostim will require a dose of < 250 µg, making the extrapolated drug cost for weekly dosing for one year approximately $55,250.

What type of drug is romiplostim?

Romiplostim is in a class of medications called thrombopoietin receptor agonists. It works by causing the cells in the bone marrow to produce more platelets.

What vitamins are good to increase platelets?

Vitamin C helps your platelets group together and function efficiently. It also helps you to absorb iron, which may also help to increase platelet counts.