What is Metastron used for?
Metastron (Strontium-89 Chloride Injection) is indicated for the relief of bone pain in patients with painful skeletal metastases. The presence of bone metastases should be confirmed prior to therapy. The recommended dose of Metastron is 148 MBq, 4 mCi, administered by slow intravenous injection (1-2 minutes).
What is strontium 89 and samarium 153?
Aetna considers the radiopharmaceuticals strontium-89 (Metastron) and samarium-153 (Quadramet) medically necessary for treatment of bone pain in cancer members with painful skeletal metastases (e.g., bone metastases from breast cancer, liver cancer, prostate cancer, or any other cancer that metastasizes to the bone) …
Who makes Metastron?
Code 330.260(a) and Part 335 Subpart F. 335.5010 or under equivalent licenses of the USNRC or an Agreement State. Manufactured by: GE Healthcare Ltd., HP7 9LL UK GE Healthcare, Medi-Physics, Inc., Arlington Heights, IL 60004 U.S.A. Metastron is a trademark of GE Healthcare.
What is the strontium 89 half-life?
Strontium-89 (Sr-89) is a pure emitter with maximum beta energy of 1.46 MeV, average beta energy of 0.58 MeV, and a physical half-life of 50.5 days.
What is strontium 89 used for?
Strontium chloride Sr 89 is used to help relieve the bone pain that may occur with certain kinds of cancer. The radioactive strontium is taken up in the bone cancer area and gives off radiation that helps provide relief of pain.
How is samarium-153 administered?
Sm-153 is administered in a 1.0-mCi/kg (37 MBq/kg) dose intravenously over the course of 1 minute. Approximately 50% of the dose is localized to bone. It accumulates in metastatic lesions in a 5:1 ratio compared with normal bone.
How is samarium-153 produced?
Samarium-153 is produced in high yield and purity by neutron irradiation of isotopically enriched samarium Sm 152 oxide (152Sm2O3). It emits both medium-energy beta particles and a gamma photon, and has a physical half-life of 46.3 hours (1.93 days).
Is strontium 89 still available?
Radiopharmaceuticals should only be used by physicians who are qualified by training and experience in the safe use and handling of radionuclides.
What’s the half-life of strontium 90?
29 years
Strontium-90 has a half- life of 29 years and emits beta particles of relatively low energy as it decays. Yttrium-90, its decay product, has a shorter half-life (64 hours) than strontium-90, but it emits beta particles of higher energy.
Is strontium 89 naturally occurring?
Strontium has physical and chemical properties similar to those of its two vertical neighbors in the periodic table, calcium and barium. It occurs naturally mainly in the minerals celestine and strontianite, and is mostly mined from these.
What is SR 89 used for?
