What does lack of agglutination mean?

The agglutination indicates that the blood has reacted with a certain antibody and therefore is not compatible with blood containing that kind of antibody. If the blood does not agglutinate, it indicates that the blood does not have the antigens binding the special antibody in the reagent.

What causes agglutination of bacterial cells?

Agglutination of bacteria One of them is opsonization. Once the antibodies detect their presence, they will “coat” the microbes, making them “sticky”. As a result, the microbial cells will agglutinate, resulting in the formation of microbial-antibody clumps.

What is the agglutination of bacteria?

Particulate antigens, such as bacteria, combine with their specific antibodies to form complexes that usually aggregate as visible clumps. This is called bacterial agglutination.

What is agglutination serology?

Agglutination is a serological reaction in which antibodies react with antigens on the surface of particles and cause the particles to clump together, or agglutinate. This reaction generally results in a visible mass that can be seen with the unaided eye.

What is agglutination in immunology?

Agglutination is defined as the formation of clumps of cells or inert particles by specific antibodies to surface antigenic components (direct agglutination) or to antigenic components adsorbed or chemically coupled to red cells or inert particles (passive hemagglutination and passive agglutination, respectively).

What is the result of agglutination?

In agglutination tests, an antigen reacts with its corresponding antibody, resulting in visible clumping of bacterial cells. With latex agglutination tests, latex particles are coated with antibodies that agglutinate specific antigens and form a more easily visible precipitate.

What causes agglutination?

Agglutination is caused by the formation of antibody-antigen complexes and occurs at room temperatures. Auto-agglutination is produced as a result of a complex formed between the patient’s own RBC antigens and antibodies, mediated by cold-reacting antibodies.

What is the importance of bacterial agglutination tests?

Agglutination can be used as an indicator of the presence of antibodies against bacteria or red blood cells.