What is z11 trial?

The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial was a multicenter noninferiority study which enrolled and randomized 891 patients with breast cancer, T1-2 disease, clinically negative axillary nodes, 1 or 2 macrometastatic nodes on SLNB, and a plan for breast conserving therapy consisting of …

What is the difference between sentinel and axillary lymph nodes?

Axillary dissection removes more nodes and disrupts more of the normal tissue in the underarm area than a sentinel node biopsy. So, it’s more likely to affect arm function and more likely to cause lymphedema. For this reason, sentinel node biopsy is the preferred method to check the axillary lymph nodes.

What is sentinel biopsy?

Sentinel node biopsy is a surgical procedure used to determine whether cancer has spread beyond a primary tumor into your lymphatic system. It’s used most commonly in evaluating breast cancer and melanoma. The sentinel nodes are the first few lymph nodes into which a tumor drains.

What is axillary lymph node clearance?

Axillary Node Clearance is an operation to remove the lymph nodes under the armpit. Breast cancer sometimes spreads to the lymph nodes, and if this has happened it is important to remove the lymph nodes to remove the cancer in your armpit.

Can swollen lymph nodes stay forever?

Following infection, lymph nodes occasionally remain permanently enlarged, though they should be non-tender, small (less the 1 cm), have a rubbery consistency and none of the characteristics described above or below.

What is axillary Inlet?

The apex is also referred to as the axillary inlet. The borders of the apex are made by the lateral surface of the first rib, the posterior surface of the clavicle, and the superior margin of the scapula. The axilla is filled with adipose (fat) and allows passage for: vessels, nerve plexus, lymphatics, and muscles.