What does letrozole do for bodybuilders?

Background: Letrozole is a potent aromatase inhibitor licensed for use in women with breast cancer. It is also used by body builders for reduction of gynecomastia when taking anabolic steroids.

Do aromatase inhibitors really work?

A new study claims a class of hormonal drugs called aromatase inhibitors may significantly reduce the risk of death among postmenopausal women with estrogen receptor-positive breast cancer – the most common form of the disease.

Does hair grow back after aromatase inhibitors?

Once treatment with aromatase inhibitors is stopped, your hair will usually grow back to its normal thickness.

Does zinc lower estradiol?

In addition, zinc deficiency alters testosterone levels and modifies sex steroid hormone receptor levels [22]. Zinc deficiency affects the enzyme complex aromatase that is normally inhibited by zinc. The increased activation results in an excessive conversion of testosterone into estradiol.

Does letrozole raise testosterone?

Letrozole improves sperm concentration and increases testosterone–oestradiol ratio for men with oligozoospermia who have normal testosterone–oestradiol ratio; its role in the treatment of male infertility may be extended to this group of patients.

Does letrozole increase follicle size?

We undertook a retrospective review of over 900 treatment cycles using letrozole in doses as high as 12.5 mg per day. Results indicate that such doses do indeed offer benefit to patients; in that there is increased follicular growth and a higher number of predicted ovulations with higher doses of the drug.

Can you take AI while on a steroid cycle?

The goal you should have is to keep your Estrogen between 20-30 pg/ml for the entirety of your cycle, regardless of what dosage of AI is necessary to achieve that. Using a predetermined dosage for your AI simply makes zero sense.

How does an AI work in the body?

An AI works through the negative feedback loop of the endocrine system. Your body see’s that you have low estrogen, which in turn, creates more testosterone to be converted by the aromatase enzyme into estrogen. BUt when the aromatase enzyme is blocked, very little of the test is converted. That’s how I understand it.

Which is the best aromatase inhibitor for bodybuilding?

Anastrozole is the leader among the above mentioned drugs. It works effectively by lowering estrogen levels in the blood, and it is well tolerated by the body. It is worth noting that Anastrozole is available in tablet form at a dosage of 1 mg.

How are aromatase inhibitors ( AIs ) related to testosterone?

AAS are structurally related to testosterone, and therefore most convert to estrogen. As a result, males that have a high amount of estrogen in the body can develop gynecomastia. Gynecomastia or “bitch tits” is male breast enlargement with lumps behind or under the nipples. This is where Aromatase Inhibitors (AIs) come in.