Do lymphatics have endothelium?

The lymphatic endothelium is a specialised form of epithelium, distinct from but similar to vascular endothelium. A lymph capillary endothelial cell is distinct from other endothelial cells in that collagen fibers are directly attached to its plasma membrane.

Where are the superficial lymphatics located?

The superficial inguinal lymph nodes reside below the inguinal ligament and subdivide into the inferior, superolateral, and superomedial nodes. The superficial inguinal lymph nodes drain the anal canal(below the pectinate line), the skin below the umbilicus, lower extremity, scrotum, and vulva.

What are superficial lymphatics?

Lymphatic vessels are both superficial and deep. The superficial vessels start in the tissue just below the skin and drain into the deep vessels that usually run alongside the blood vessels. The ones that carry lymph away from lymph nodes are called efferent lymphatic vessels.

Does cartilage have lymphatics?

Lymphatic vessels have been found in almost every tissue. Exceptions have traditionally included bone marrow, cartilage, the cornea, and the central nervous system. However, even within these tissues there has been evidence of lymphatic drainage under normal conditions, or lymphangiogenesis under pathologic conditions.

What is lymphatic endothelial cell?

Lymphatic endothelial cells (LECs) form the structure of the lymphatic vessels and the sinuses of the lymph nodes, positioning them to be key players in many different aspects of the immune response. Following an inflammatory stimulus, LECs produce chemokines that recruit immune cells to the lymph nodes.

Where are lymph nodes in the lower legs?

There are four lymphatic pathways in the lower leg (anteromedial, anterolateral, posterolateral, and posteromedial) that drain mainly to three lymph nodes; two nodes were in the superficial inguinal region and one node was in the popliteal region.

Are there lymph nodes below the knee?

Lymph nodes are located throughout your body in your neck, underarms and groin and behind your knees. They are also deeper inside your body in your chest, abdomen and pelvic area.

How do initial lymphatics differ from lymph vessels?

Afferent lymphatic vessels flow into a lymph node and carry unfiltered lymph fluid. Efferent lymphatic vessels flow out of a lymph node and carry filtered lymph fluid. Lymph vessels that leave the thymus or spleen (which lack afferent vessels) also fall into this category.