What are the most common side effects of hydralazine?

Headache, pounding/fast heartbeat, loss of appetite, nausea, vomiting, diarrhea, or dizziness may occur as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Is hydralazine and Dihydralazine same?

Pharmacology. Hydralazine and dihydralazine are structurally similar vasodilator drugs that have been used for the treatment of hypertension in pregnancy for over 40 years. Following oral administration, up to 80 percent absorption occurs, and approximately 66 percent of the drug is deactivated in the liver.

Is hydralazine a safe blood pressure medication?

Don’t stop taking hydralazine suddenly. Doing so may lead to uncontrolled high blood pressure. It can raise your risk for heart problems, such as chest pain or heart attack.

Is hydralazine bad for kidneys?

A new case study supports previous findings that hydralazine — a medication used to treat high blood pressure — may cause ANCA-associated vasculitis with severe kidney injury, leading its researchers to recommend its use “generally be avoided.”

What is the best time of day to take hydralazine?

If you are to take a single dose a day, take it in the morning after breakfast. If you are to take more than one dose a day, take the last dose no later than 6 p.m., unless otherwise directed by your doctor.

What drugs contain hydralazine?

Hydralazine

  • Brand names: Apresoline. Drug class(es): vasodilators.
  • Brand names: Hydra-Zide, HydrALAZINE Plus, Apresazide. Drug class(es): miscellaneous antihypertensive combinations.
  • Brand names: Diuretic Ap-Es, Ser-Ap-Es, Serpazide, Uni Serp. Drug class(es): miscellaneous antihypertensive combinations.
  • Brand names: BiDil.

Is hydralazine bad for your kidneys?

Hydralazine is a vasodilator used to treat high blood pressure (hypertension) since the 1950s. But the medication is not without side effects, and studies have reported that 5 to 8% of patients who use hydralazine develop lupus, and 5 to 10% develop renal injury.

When should you not take hydralazine?

You should not use hydralazine if you are allergic to it, or if you have: coronary artery disease; or. rheumatic heart disease affecting the mitral valve….To make sure hydralazine is safe for you, tell your doctor if you have ever had:

  1. kidney disease;
  2. systemic lupus erythematosus;
  3. angina (chest pain); or.
  4. a stroke.

How quickly does hydralazine lower blood pressure?

BP-lowering effect occurs in 20–30 minutes following oral administration, 10–30 minutes following IM administration, and 5–20 minutes following IV administration. BP-lowering effect lasts for 2–4 hours following oral administration or 2–6 hours following IM or IV administration.

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