How accurate is an MIBG scan?
The overall sensitivity of 131I-MIBG scanning was 77%, specificity was 96%, and accuracy was 86%. This test is fairly sensitive in the workup of patients with known or suspected recurrent or metastatic pheochromocytoma.
What does a MIBG scan show?
Definition: MIBG is a nuclear scan test that uses injected radioactive material (radioisotope) and a special scanner to locate or confirm the presence of pheochromocytoma and neuroblastoma, which are tumors of specific types of nervous tissue.
What is MIBG uptake?
Iodine 123 (123I) metaiodobenzylguanidine (MIBG) is the first-line functional imaging agent used in neuroblastoma imaging. MIBG uptake is seen in 90% of neuroblastomas, identifying both the primary tumor and sites of metastatic disease.
What is Dotatate scan?
A Dotatate PET scan is used to evaluate neuroendocrine tumors (NETs). These tumors can occur throughout the body. How does it work? A small amount of a radioactive drug called Dotatate is given by injection before the PET scan.
What is a Curie score?
A score of 3 was assigned for the soft-tissue region if disease occupied >50% of the chest or abdomen. A patient’s Curie score at each time point was calculated as the sum of scores over all individual sites, with a maximum score of 30.
How long does it take to get results from MIBG scan?
The test is done in stages and takes 2 to 4 days to complete. On the first day you will have the radioactive MIBG injected into a vein in your arm or hand.
What is GA 68 Dotatate used for?
Gallium Ga 68 dotatate injection is used with a PET scan (positron emission tomography) for localization of somatostatin receptor positive neuroendocrine tumors (NETs) in adults and children.
What is krenning score Dotatate?
The Krenning score is used to grade the uptake intensity of neuroendocrine tumors on somatostatin receptor imaging such as octreotide scan. Typically, peptide receptor radionuclide therapy (PRRT) is considered when the Krenning score is greater than 2.
What is MIBG Curie score?
Conclusions: MIBG scoring is a useful tool in identifying pts with extremely poor prognosis following induction therapy. Patients with a Curie score > 5 after induction have a 3 yr EFS < 10%, and should be considered for alternative therapy regimen.
