What happens to acetyl CoA in the electron transport chain?
The acetyl group of acetyl-CoA enters the citric acid cycle. For each acetyl-CoA that enters the citric acid cycle, 2 molecules of carbon dioxide, 3 molecules of NADH, 1 molecule of ATP, and 1 molecule of FADH2 are produced. The pH gradient produced by the electron transport chain drives the synthesis of ATP from ADP.
How is the citric acid cycle connected to electron transport?
The citric acid cycle is a series of chemical reactions that removes high-energy electrons and uses them in the electron transport chain to generate ATP. As the electrons are passed from NADH or FADH2 down the electron transport chain, they lose energy. The products of the electron transport chain are water and ATP.
Where does acetyl CoA formation and the citric acid cycle take place in the cell?
mitochondria
Most fuel molecules enter the cycle as acetyl CoA. The link between glycolysis and the citric acid cycle is the oxidative decarboxylation of pyruvate to form acetyl CoA. In eukaryotes, this reaction and those of the cycle take place inside mitochondria, in contrast with glycolysis, which takes place in the cytosol.
Which products of the citric acid cycle will proceed to the electron transport chain?
These products from the citric acid cycle are made in the mitochondria of your cells.. During oxidative phosphorylation, NADH and FADH 2start subscript, 2, end subscript are transported to the electron transport chain, where their high energy electrons will ultimately drive synthesis of ATP.
Where does acetyl CoA formation occur?
Acetyl-CoA Formation. Acetyl-CoA formation occurs inside or outside the cell mitochondria. As a metabolite (a substance necessary for metabolism), acetyl-CoA must be freely available. It can be produced via the catabolism (breakdown) of carbohydrates (glucose) and lipids (fatty acids).
What is the function of acetyl-CoA in the citric acid cycle?
acetyl CoA: Acetyl coenzyme A or acetyl-CoA is an important molecule in metabolism, used in many biochemical reactions. Its main function is to convey the carbon atoms within the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized for energy production.
What activates the citric acid cycle?
The citric acid cycle is regulated primarily by the concentration of ATP and NADH. The key control points are the enzymes isocitrate dehydrogenase and α-ketoglutarate dehydrogenase. Isocitrate dehydrogenase is allosterically stimulated by ADP, which enhances the enzyme’s affinity for substrates.
What is the formation of acetyl CoA?
The acetyl CoA is formed from the end product of glycolysis i.e. pyruvate. The formation of acetyl CoA takes place with the help of the enzyme pyruvate dehydrogenase and coenzyme A. During the breakdown of pyruvate, electrons are transferred to NAD+ to produce NADH, which will be used by the cell to produce ATP.
What cycle or pathway does acetyl CoA enters?
citric acid cycle
Acetyl CoA is a molecule that is further converted to oxaloacetate, which enters the citric acid cycle (Krebs cycle). The conversion of pyruvate to acetyl CoA is a three-step process.
