What does endochondral ossification literally mean?

: ossification taking place from centers arising in cartilage and involving deposition of lime salts in the cartilage matrix followed by secondary absorption and replacement by true bony tissue — compare intermembranous ossification.

How do you explain endochondral ossification?

Endochondral ossification involves the replacement of hyaline cartilage with bony tissue. Most of the bones of the skeleton are formed in this manner. These bones are called endochondral bones. In this process, the future bones are first formed as hyaline cartilage models.

What are the 7 steps of endochondral ossification?

7 steps:

  • Development of the cartilage model.
  • Growth of the cartilage model.
  • Development of the primary ossification center.
  • Development of the Medullary cavity.
  • Secondary ossification centers.
  • Formation of articular cartilage & epiphyseal plate.
  • Closure of Growth Plate (epiphyseal plate hardens)

What are the 6 steps of endochondral ossification?

Terms in this set (6)

  • Cartilage enlarges; Chondrocytes die.
  • blood vessels grow into perichondrium; cells convert to osteoblasts; shaft becomes covered with superficial bone.
  • more blood supply and osteoblasts; produces spongy bone; formation spreads on shaft.
  • Osteoclasts create medullary cavity; appositional growth.

Are ribs Endochondral?

Endochondral bone: Any bone that develops in and replaces cartilage. Many bones are formed this way, particularly the long bones of the arms, legs, and ribs. “Endochondral” means “within cartilage.”

What does Endosteum mean?

: the layer of vascular connective tissue lining the medullary cavities of bone.

What is the meaning of Endochondral?

Endochondral bone: Any bone that develops in and replaces cartilage. The cartilage is partially or entirely destroyed by the process of calcification. Many bones are formed this way, particularly the long bones of the arms, legs, and ribs. “Endochondral” means “within cartilage.”

Is the femur formed by endochondral ossification?

3.1 Endochondral Ossification. Endochondral ossification is the process by which bone tissue is formed in early fetal development. It begins when MSCs start to produce a cartilage template of long bones, such as the femur and the tibia, upon which bone morphogenesis occurs.

What bones are formed by endochondral ossification?

Endochondral ossification is the process of bone development from hyaline cartilage. All of the bones of the body, except for the flat bones of the skull, mandible, and clavicles, are formed through endochondral ossification. In long bones, chondrocytes form a template of the hyaline cartilage diaphysis.

What are the 5 stages of endochondral ossification?

Endochondral Ossification

  • Reserve Zone. Storage site for lipids, glycogen, proteoglycan.
  • Proliferative Zone. Proliferating chondrocytes leading to longitudinal growth.
  • Hypertrophic Zone. Site of chondrocyte maturation.
  • Primary Spongiosa. Site for mineralization to form woven bone.
  • Secondary Spongiosa.

Which bones are formed by endochondral ossification?

Which bones are Endochondral?

Endochondral ossification is the process of bone development from hyaline cartilage. All of the bones of the body, except for the flat bones of the skull, mandible, and clavicles, are formed through endochondral ossification.