What does a positive cardiolipin IgG mean?

A positive result means that cardiolipin antibody was detected in the blood. As mentioned earlier, the presence of cardiolipin antibodies may indicate several diseases, such as: Syphilis. Antiphospholipid syndrome (APS) Systemic lupus erythematosus (SLE)

What is cardiolipin antibodies test for?

Cardiolipin antibody testing is typically ordered as part of excessive clotting workup when an individual has symptoms suggestive of a blood clot (thrombotic episode), especially when they recur. Signs and symptoms vary, depending on the location of the clot.

What does a high cardiolipin IgM mean?

The levels of these antibodies are often high in people with abnormal blood clotting, autoimmune diseases like systemic lupus erythematosus (SLE), or repeated miscarriages.

What is the difference between IgG and IgA antibodies?

Immunoglobulin A (IgA): It’s found in the linings of the respiratory tract and digestive system, as well as in saliva (spit), tears, and breast milk. Immunoglobulin G (IgG): This is the most common antibody. It’s in blood and other body fluids, and protects against bacterial and viral infections.

What is cardiolipin IgA?

Clinical Significance Cardiolipin Antibodies (IgA, IgG, IgM) – Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly systemic lupus erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion.

What are normal levels of cardiolipin?

Reference Interval

What is normal range for cardiolipin?

Reference range: IgG anticardiolipin: Weak positive: 15-40U/ml. Positive: >40U/ml.

What does it mean if you have IgG and IgM antibodies?

When IgM antibodies are present, they can indicate that a patient has an active or recent infection with SARS- CoV-2. IgG antibodies develop later following infection, and generally do not begin to appear until 7 – 10 days after infection.

What are the causes of low IgG and IgM?

Low levels of the IgG antibody can also be caused by Waldenstrom’s macroglobulinemia, a rare blood cancer that is characterized by an overproduction of the IgM antibody and subsequent suppression of production of other types of antibodies, including IgG.

What are anticardiolipin antibodies?

Anticardiolipin antibodies are antibodies that the body creates to target cardiolipin and phospholipid. Cardiolipin is a part of the inner section of the mitochondrial membrane in cells.

Is IgM past or present?

While IgM is an indicator of a current infection, an IgG indicates a recent or past exposure to the illness. IgM is the first antibody that the body produces in an acute infection. It is approximately six times larger than IgG and is multivalent.

What is cardiolipin antibody syndrome?

Cardiolipin antibodies are bodily defense proteins that mistakenly target host phospholipids. They are one of the several antiphospholipid antibodies, responsible for causing antiphospholipid syndrome (APS) Phospholipids are a type of fat molecules comprising the membranes of cells.