Can osteoarthritis cause bone lesions?

In addition to bone shape or morphology, the pathologic bone abnormalities found in OA are also thought to be important biomechanically. The bony lesion most studied to date in this regard is BMLs.

What makes up subchondral bone?

Subchondral bone is composed of two types of lamellae: concentric lamellae around the osteons and flat lamellae. SBP, like compact bone, is composed of subunits called osteons consisting of concentric lamellae surrounding the central (Haversian) canal.

What is the function of subchondral bone?

The function of the subchondral bone is to attenuate forces generated through locomotion, with the compact subchondral bone plate providing firm support and the subchondral trabecular component providing elasticity for shock absorption during joint loading (3).

What happens to subchondral bone in osteoarthritis?

In osteoarthritis, the subchondral bone becomes thicker than usual. Evidence has suggested that the thickening happens before the articular cartilage starts to wear away—an indication that subchondral bone plays a role in the development of osteoarthritis.

Can a bone lesion be arthritis?

Bone marrow lesions are parts of the bone which are linked to pain in osteoarthritis. The genes found are involved in new nerve formation, pain sensitization, bone and cartilage renewal.

What does subchondral mean in medical terms?

“Subchondral bone” is bone that sits underneath cartilage in a joint. Subchondral bone is found in large joints like the knees and hips, as well as in small joints like those of the hands and feet. “Sclerosis” refers to an unusual increase in the density or hardness of a tissue in the body.

Where is subchondral bone found?

What Is Subchondral Bone? Subchondral bone is the layer of bone just below the cartilage in a joint. the -chondral refers to cartilage, while the prefix sub means below. Subchondral bone is a shock absorber in weight-bearing joints.

Do benign bone lesions hurt?

Benign tumors may be painless, but often they cause bone pain. The pain can be severe. Pain may occur when at rest or at night and tends to progressively worsen.

What is subchondral bone damage?

Subchondral bone supports overlying articular cartilage and distributes mechanical loads across joint surfaces with a gradual transition in stress and strain. Stiffened and less pliable subchondral bone could transmit increased loads to overlying cartilage, leading to secondary cartilage damage and degeneration [11].

What are the symptoms of subchondral sclerosis?

Patients with subchondral sclerosis may feel symptoms as follows: pressure and pain within the bone. painful bone spurs. a reduce motion range in the affected joint. the loss of height, especially if the knee, hip, or spine are affected. the locking of the joint when subchondral sclerosis occurs in the knee.

What are subchondral cystic changes?

Early DJD: Subchondral cysts mean cysts in the bone underneath the cartilage, and are a reaction of the bone to degenerative and stress related changes about the joint space. These are usually seen with some cartilage damage and narrowing of the joint space adjacent to the cyst.

What is the lesion doing to the bone?

Also known as bone lesions or osteolytic lesions, lytic lesions are spots of bone damage that result from cancerous plasma cells building up in your bone marrow. Your bones can’t break down and regrow (your doctor may call this remodel) as they should. This makes them thin and creates areas of weaker bones that are vulnerable to fractures.

What are subchondral cysts?

Subchondral bone cysts (SBCs) are sacs filled with fluid that form inside of joints such as knees, hips, and shoulders.