Is Aranesp dialyzed?

Not on dialysis: Q2W recommended starting dose: 0.75 mcg/kg as an IV or SC injection once every 2 weeks, as appropriate.

When should Aranesp be given during dialysis?

For Adult Patients With CKD On Dialysis Initiate Aranesp treatment when the hemoglobin level is less than 10 g/dL. If the hemoglobin level approaches or exceeds 11 g/dL, reduce or interrupt the dose of Aranesp.

What is Aranesp injection used for?

This medication is used to treat anemia (low red blood cell count) in people with long-term serious kidney disease (chronic kidney failure) and people receiving chemotherapy for some types of cancer (cancer that does not involve the bone marrow or blood cells).

Can Aranesp be given IV?

Aranesp™ is formulated as a sterile, colorless, preservative-free protein solution for intravenous (IV) or subcutaneous (SC) administration. Single-dose vials are available containing 25, 40, 60, 100, 150, 200, 300, or 500 mcg of Aranesp™.

How is Aranesp injection given?

Aranesp can be injected directly into a layer of fat under your skin. This is called a subcutaneous injection. When giving subcutaneous injections, follow your healthcare provider’s instructions about changing the site for each injection.

How long does Aranesp last?

You can use Aranesp if it has been left out of the refrigerator, for no longer than 2 days at room temperature (up to 30°C). Do not use Aranesp if you think that it has been frozen for longer than 2 days. You can use Aranesp if accidentally left frozen for less than 2 days.

Where do you inject Aranesp?

Aranesp can be injected directly into a layer of fat under your skin. This is called a subcutaneous injection.

How effective is Aranesp?

ARANESP Is Effective and More Convenient for Controlling Anemia. SAN FRANCISCO-The anemia drug darbepoetin alfa (ARANESP) effectively alleviates anemia, boosting hemoglobin counts and reducing the need for red blood cell transfusions, according to the results of two separate studies.

What’s the lowest dose of Aranesp you can take?

ARANESP ® SINGLEJECT ® PREFILLED SYRINGES greater than 11 g/dL. not increase these risks. Individualize dosing and use the lowest dose of Aranesp ® sufficient to reduce the need for RBC transfusions.

Can you take Aranesp in a prefilled syringe?

Aranesp ® is available in single-dose vials and prefilled syringes, except the 10, 150, and 500 mcg dose strengths, which are available only as prefilled syringes. The IV route of administration is recommended for adult patients on hemodialysis. *Except 15 mcg dose.

How often should you take Aranesp for chronic kidney disease?

Here’s an example how 1: Pinch to zoom. Pinch to zoom. Hb = hemoglobin; QW = once weekly; Q2W = once every 2 weeks; TIW = 3 times weekly; IV = intravenous; CKD = chronic kidney disease; DCR = dose conversion ratio; ESA = erythropoiesis-stimulating agent; RBC = red blood cell count; Q4W = once every 4 weeks; SC = subcutaneous.

Are there any side effects to taking Aranesp?

Darbepoetin alfa can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use Aranesp. Seek emergency medical help if you have: heart attack symptoms – chest pain or pressure, shortness of breath, pain spreading to your jaw or shoulder, nausea, sweating;