What is the KPC infection?

Abstract. Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria are a group of emerging highly drug-resistant Gram-negative bacilli causing infections associated with significant morbidity and mortality.

How do you get infected with Klebsiella?

Klebsiella bacteria are mostly spread through person-to-person contact. Less commonly, they are spread by contamination in the environment. As with other healthcare-associated infections, the bacteria can be spread in a health care setting via the contaminated hands of health care workers.

What antibiotics treat Klebsiella?

Therapeutic choices include aminoglycosides, tetracycline, sulfonamides, rifampin, and quinolones. Ozena may be treated with a 3-month course of ciprofloxacin. Intravenous aminoglycosides and trimethoprim/sulfamethoxazole are also useful in the treatment of these conditions.

How serious is Klebsiella pneumoniae UTI?

But klebsiella pneumoniae can be dangerous if they get into other parts of your body, especially if you’re already sick. They can turn into “superbugs” that are almost impossible to fight with common antibiotics. The germs can give you pneumonia, infect your wound or blood, and cause other serious problems.

How common is Klebsiella?

In the United States, Klebsiella pneumoniae and Klebsiella oxytoca are the two strains responsible for most human illnesses. Many Klebsiella infections are acquired in the hospital setting or in long-term care facilities. In fact, Klebsiellae account for up to 8% of all hospital-acquired infections.

How do you get rid of gut Klebsiella?

Treatment for KO is like any other infection and involves antibiotics. Some strains of KO can be antibiotic-resistant. That means the most frequently used antibiotics will not be effective against the bacteria.

What kills klebsiella bacteria?

Doctors treat K. pneumoniae infections with antibiotics. When an infection is hospital-associated, doctors use a class of antibiotics called carbapenems until results of sensitivity testing are available.

What are the symptoms of Klebsiella pneumoniae in urine?

Klebsiellae UTIs are clinically indistinguishable from UTIs caused by other common organisms. Clinical features include frequency, urgency, dysuria, hesitancy, low back pain, and suprapubic discomfort. Systemic symptoms such as fever and chills are usually indicative of a concomitant pyelonephritis or prostatitis.

Where does Klebsiella pneumoniae carbapenemase ( KPC )-producing bacteria?

Abstract. Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria are a group of emerging highly drug-resistant Gram-negative bacilli causing infections associated with significant morbidity and mortality. Once confined to outbreaks in the northeastern United States (US), they have spread throughout the US and most of the world.

Is there any treatment for KPC-producing bacteria?

With the spread of KPC-producing bacteria, clinicians are becoming increasingly dependent on polymyxins and tigecycline for treatment of these infections. Some experts suggest that high-dose continuous infusion of a carbapenem may be helpful, though clear evidence of efficacy is lacking.

Who is at risk for infection with KPC?

Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae is spreading globally and represents a challenge in infection control and treatment. Solid organ transplant (SOT) recipients are especially at risk for infection by multidrug-resistant bacteria, and little is known about infection with KPC-producing organisms in this setting.

What are the symptoms of KPC superbacterium?

The symptoms of KPC bacterium Klebsiella pneumoniae carbapenemase may include: 1 Febre above 39ºC, 2 Increase in heart rate; 3 Difficulty to breathe; 4 Urinary tract pneumonia; 5 urinary tract infection, mainly in pregnancy.