What are the three metabolic fates of pyruvate?

– Acetyl CoA, which is a substrate for the citric acid cycle and fatty acid synthesis. – Oxaloacetate, which is an intermediate in the citric acid cycle and also a substrate for gluconeogenesis. – Lactate, which is produced by eukaryotes in the absence of oxygen.

What are the different metabolic fates of pyruvate?

The oxidation of glucose and, to a much smaller degree, the deamination of alanine, generates pyruvate, which has four metabolic fates: (1) enter mitochondria and be oxidized to acetyl-CoA via pyruvate dehydrogenase. (2) Enter mitochondria and be carboxylated to form oxaloacetate via pyruvate carboxylase.

What is are possible metabolic fates of pyruvate in humans?

Under aerobic conditions, pyruvate is oxidized to acetyl-CoA and passes through the citric acid cycle. Under anaerobic conditions, pyruvate is reduced to lactate to recycle NADH to NAD+, allowing the continuation of glycolysis.

What are the possible fates of pyruvate in glycolysis?

Pyruvate can enter in lactic acid fermentation and alcoholic fermentation in anaerobic condition, in aerobic condition pyruvate loss hydrogen and carbon dioxide and convert into acetyl CoA and enter into the TCA cycle, and also enter into the biosynthetic pathway.

What are the three possible fates of pyruvate quizlet?

Fates of Pyruvate

  • conversion to acetyl CoA by PDH.
  • conversion to lactate by lactate dehydrogenase.
  • conversion to oxaloacetate by pyruvate carboxylase.

What are the possible metabolic fates of pyruvate quizlet?

Terms in this set (11)

  • pyruvate to acetyl-coA to citric acid cycle. Fate of pyruvate under aerobic conditions (Oxygen is available) in any cell type.
  • pyruvate to lactate/lactic acid.
  • pyruvate to acetaldehyde to ethanol.
  • pyruvate dehydrogenase complex.
  • lactate dehydrogenase.
  • pyruvate decarboxylase.
  • alcohol dehydrogenase.
  • NAD+

What are the 5 fates of pyruvate?

Terms in this set (6)

  • Fate 1. Remove. Reduce. Alcohol fermentation. co2.
  • Fate 2. Reduced by. Lactate fermentation. Nadh.
  • Fate 3. Process. Inhibits. Alanine cycle. Gluconeo.
  • Fate 4. Oxidised. Acetyl coa formation. Pyruvate to co2 and h2o.
  • Fate 5. Process. Oxaloacetate. Atp. Anabolic.
  • Pyruvate dehydrogenase needs. O2 to let pyruvate into cell.

What are the four fates of pyruvate?

What are the fates of pyruvate in cells?

The fate of pyruvate depends on cell type and metabolic conditions. There are three main destinations for pyruvate: (1) aerobic organisms and tissues, under aerobic conditions – pyruvate is oxidized, with loss of the carboxylic group, resulting in the acetyl group from acetyl-CoA, which is then oxidized to CO2 in the Krebs cycle;

What are the three main destinations of pyruvate?

The fate of pyruvate depends on cell type and metabolic conditions. There are three main destinations for pyruvate:

How is pyruvate used in the TCA cycle?

Pyruvate is an intermediate compound in the metabolism of fats, proteins, and carbohydrates. It can be formed from glucose via glycolysis or the transamination of alanine. It can be converted into Acetyl-CoA to be used as the primary energy source for the TCA cycle, or converted into oxaloacetate to replenish TCA cycle intermediates.

How is pyruvate used in the digestive system?

Pyruvate Metabolism. Pyruvate is an intermediate compound in the metabolism of fats, proteins, and carbohydrates. It can be formed from glucose via glycolysis or the transamination of alanine. It can be converted into Acetyl-CoA to be used as the primary energy source for the TCA cycle, or converted into oxaloacetate to replenish TCA cycle