What is bilateral Perisylvian polymicrogyria?

Bilateral perisylvian polymicrogyria (BPP) is a rare neurological disorder that affects the cerebral cortex (the outer surface of the brain). BPP is a subtype of a broader condition known as polymicrogyria. The cerebral cortex of the brain normally consists of several deep folds and grooves.

What does the Perisylvian region do?

the area of the brain that is responsible for language. It consists of the region around the lateral sulcus (Sylvian fissure) of the left hemisphere and includes Broca’s area and Wernicke’s area. Damage to the zone causes various forms of aphasia.

What is Perisylvian syndrome?

Perisylvian syndrome is a rare neurological disease characterized by damage to the sylvian fissure (lateral sulcus), an area in the brain involved in language and speech.

What does Perisylvian mean?

Is Polymicrogyria genetic?

Polymicrogyria can result from both genetic and environmental causes. It may occur as an isolated finding or as part of a syndrome . Treatment is based on the signs and symptoms present in each person.

Where is the Perisylvian zone?

What are symptoms of global aphasia?

Global aphasia is the most severe form of aphasia. It can cause symptoms affecting all aspects of language ability. People with global aphasia have the inability or extreme difficulty of reading, writing, understanding speech, and speaking. Some people with global aphasia can answer basic yes or no questions.

Is there such a thing as bilateral perisylvian polymicrogyria?

Bilateral perisylvian polymicrogyria also called congenital bilateral perisylvian syndrome, is a rare neurological disorder that affects the cerebral cortex (the outer surface of the brain) 6). Bilateral perisylvian polymicrogyria is a subtype of a broader condition known as polymicrogyria.

What kind of brain disorder is bilateral polymicrogyria?

Bilateral frontoparietal polymicrogyria is a rare neurological disorder that affects the cerebral cortex (the outer surface of the brain). Bilateral frontoparietal polymicrogyria specifically affects the frontal and parietal lobes on both sides of the brain (bilateral).

What are the signs and symptoms of polymicrogyria?

Signs and symptoms of these conditions can include recurrent seizures (epilepsy), delayed development, crossed eyes, problems with speech and swallowing, and muscle weakness or paralysis. The most severe form of the disorder, bilateral generalized polymicrogyria, affects the entire brain.

What can be done to treat perisylvian polymicrogyria?

For example, anti-seizure medications may help control seizures 11). The quality of life and life expectancy for people with bilateral perisylvian polymicrogyria are not well-described but may depend on severity of symptoms, whether complications develop, and whether other birth defects or an underlying syndrome are present 12). Figure 1.