What are serum indices?
Liquichek Serum Indices is intended for use as part of laboratory interference testing to monitor an instrument’s response in detecting hemolyzed, icteric or lipemic (HIL) samples to help improve detection of pre-analytical errors affecting clinical chemistry testing.
How does icterus affect CBC results?
Icterus has minimal to no effect on hematologic results, including plasma protein measured by refractometry (Gupta & Stockham 2014).
How does icterus affect lab results?
Visual inspection results for icterus showed more variations between technologists and compared to ordinal values. Conclusions: We have demonstrated that some of the chemistry analytes were affected by hemolysis, icterus and lipemia interferences. Generally, our results were consistent with manufacturer’s claims.
What is icterus blood sample?
Icterus, also known as jaundice, is used to describe the yellowish-greenish color observed in the sclera of the eyes or in plasma/serum samples of patients with very high concentrations of bilirubin. The form of bilirubin found in patient samples also depends on the patient’s disease.
How are serum indices measured?
The Serum Indices Gen. 2 assay is based on calculations of absorbance measurements of diluted samples at different dichromatic wavelength pairs to provide a semi-quantitative representation of levels of lipemia, hemolysis and icterus present in serum and plasma samples.
What is Hil index?
The HIL alert index (also known as the threshold level) is defined as the lowest concentration of HIL that interferes with chemical analyses, yielding a bias >10% [2]. However, the methods of reporting HIL status, such as value and index, differ depending on the specific chemical analyzers.
What is the difference between jaundice and icterus?
Icterus is also known as jaundice or yellow jaundice. It refers to an excessive accumulation of a yellow pigment in the blood and tissues. When icterus has been present for any length of time, it will discolor many tissues and will become visible as jaundice on most body surfaces, including the skin.
What causes specimen icterus?
Icteric serum is caused by the presence of excess bilirubin in the blood stream. Icteric serum is caused by the presence of excess bilirubin in the blood stream as a result of increased production (pre-hepatic) or inappropriate excretion (hepatic and post-hepatic).
What causes specimen Icteric?
What is icteric serum?
The final discolouration of the serum we are going to cover is icteric serum. Icteric serum is caused by the presence of excess bilirubin in the blood stream as a result of increased production (pre-hepatic) or inappropriate excretion (hepatic and post-hepatic).
What is Icteric serum?
How is the Icterus index related to hyperbilirubinemia?
Icteric index The number reported under icterus is an estimation of the total bilirubin concentration in mg/dL rounded to the nearest whole number. The icterus index can be used to determine if there is hyperbilirubinemia, i.e. if the total bilirubin is increased, the icteric index should closely match the value seen.
What can liquichek serum indices be used for?
Description Liquichek Serum Indices is intended for use as part of laboratory interference testing to monitor an instrument’s response in detecting hemolyzed, icteric or lipemic (HIL) samples to help improve detection of pre-analytical errors affecting clinical chemistry testing. To learn more visit: www.qcnet.com/serumindices
How are hemolysis and icteric indexes measured?
In our core laboratory, all samples processed by our automation system have serum indices measured spectrophotometrically, which include an H-index (hemolysis), I-index (icterus), and L-index (lipemia/turbidity).
What does Icterus stand for in medical terms?
Here, we discuss special considerations for detecting and reporting results on icteric samples that exceed the acceptable I-index cutoff. Icterus, also known as jaundice, is used to describe the yellowish-greenish color observed in the sclera of the eyes or in plasma/serum samples of patients with very high concentrations of bilirubin.
