How is Omphalitis treated?

A combination of parenterally administered antistaphylococcal penicillin and an aminoglycoside antibiotic is recommended for uncomplicated omphalitis. Intravenous antimicrobial therapy with clindamycin or metronidazole may be indicated in some cases.

What is persistent neonatal hypoglycemia?

Newborn with Persistent Hypoglycemia. Definition: Inability to consistently maintain. pre-prandial glucose concentration: > 50 mg/dL up to 48 hrs of life OR. > 60 mg/dL after 48 hrs of life.

What is Omphalitis of the newborn?

Omphalitis is an infection of the umbilicus and/or surrounding tissues, occurring primarily in the neonatal period. It is a true medical emergency that can rapidly progress to systemic infection and death, with an estimated mortality rate between 7 and 15 percent.

What are signs of Omphalitis?

What are the signs of omphalitis?

  • Pus or a fluid-filled lump on or near the umbilical cord stump.
  • Red skin spreading from around the navel.
  • Abdominal swelling.
  • Cloudy foul-smelling discharge from the infected region.
  • Fever (Caution: Do not give your baby any fever medicine without approval from the pediatrician)

What causes newborn hypoglycemia?

Hypoglycemia can be caused by conditions such as: Poor nutrition for the mother during pregnancy. Making too much insulin because the mother has poorly controlled diabetes. Incompatible blood types of mother and baby (severe hemolytic disease of the newborn)

What is the treatment for neonatal hypoglycemia?

Treatment includes giving the baby a fast-acting source of glucose. This may be as simple as a glucose and water mixture or formula as an early feeding. Or your baby may need glucose given through an IV. The baby’s blood glucose levels are checked after treatment to see if the hypoglycemia occurs again.

What is neonatal Omphalitis?

What causes Omphalitis?

Omphalitis is a bacterial infection of the umbilical stump that presents around day 3 of life. It is commonly caused by S. aureus, Staphylococcus epidermidis, Streptococcus species (spp)., Escherichia coli, Clostridium difficile, Klebsiella, and Pseudomonas.

How is Neonatal hypoglycemia related to pregnancy?

Factors related to transient hypoglycemia are often related to conditions or events occurring during birth. Infants of mothers receiving intravenous dextrose during delivery and those treated with hypoglycemic agents during pregnancy have been linked to neonatal hypoglycemia.

How are transient and persistent hypoglycemia related?

TRANSIENT VERSUS PERSISTENT HYPOGLYCEMIA Factors related to transient hypoglycemia are often related to conditions or events occurring during birth. Infants of mothers receiving intravenous dextrose during delivery13and those treated with hypoglycemic agents during pregnancy14have been linked to neonatal hypoglycemia.

What should glucose infusion rates be for hypoglycemic infants?

Glucose infusion rates should be titrated to achieve euglycemia, and hypoglycemic infants may require considerably higher rates. Dextrose concentrations of up to 20% to 25% may be required in order to deliver glucose infusion rates in the 15 to 30 mg/kg/min range.

How is diazoxide used for hypoglycemia in infants?

Several other agents may be valuable for management of infants in whom the diagnosis of hyperinsulinemia is confirmed and who remain persistently hypoglycemic in spite of administration of IV glucose at 15 to 20 mg/kg per minute. Diazoxide at a dose of 5 mg/kg every 8 hours will inhibit pancreatic insulin secretion.